DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and UBP9

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_192795.3	Gene:	UBP9 / 826649	AraportID:	AT4G10570	Length:	923	Species:	Arabidopsis thaliana

Alignment Length:	779	Identity:	145/779 - (18%)
Similarity:	226/779 - (29%)	Gaps:	340/779 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ERKAIHCNCFECGSYGIQLY-ACLH---------------------------CIYFGC--RGAHI 72
            |||.| |..|...||.:::| .||.                           |...|.  ..|||
plant   130 ERKLI-CQGFYTRSYSVEVYPLCLMLTDGRDESRTVIRLGKQASIRELYEKVCAMTGVPQEKAHI 193

  Fly    73 TSHLRSKKHNVALELSHGTL---YCYACRDFIYD-------------ARSREYALINRKLEAKDL 121
            ..:...:|:.:...||:.:|   ..:..:|.:.:             :...|.||:  .||.
plant   194 WDYFDKRKNGLLDPLSYKSLEESSLHMDQDILVEVDGLSSSSQSAMSSTGNELALV--PLEP--- 253

  Fly   122 QKSIGWVPWVPTTKETNLLLAN------------ARRRL--VRPNQTIGLRGLLNLGATCFMNCI 172
            .:||..:...||....:...:|            .|..|  :...:..||.||.|||.|||||..
plant   254 SRSIVTIAGGPTLSNGHSTTSNFSLFPRITSEDDGRDSLSILGKGEKGGLAGLSNLGNTCFMNSA 318

  Fly   173 VQALVHTPLLSDYFMSDRHD----------CGSKSSHKCLVCEVSRLFQEFYSGSRSPLSLHRLL 227
            :|.|.|||.:.:||:.|..|          ||.      |......|.::.:|..|:.::.....
plant   319 LQCLAHTPPIVEYFLQDYSDDINRDNPLGMCGE------LAIAFGDLLKKLWSSGRNAVAPRAFK 377

  Fly   228 HLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYG 292
            ..:...|...:||.|.|:.|.....||.||....|.|.:...:...|.|......:....::...
plant   378 TKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLNKVKRKPYIELKDSDSRPDDEVAEELWNYHKA 442

  Fly   293 QCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTT-------------------- 337
            :.:.:|..:..|..:|.:||..|..:|.|:|||..:|:.|..|.|
plant   443 RNDSVIVDVCQGQYKSTLVCPVCGKISITFDPFMYLSVPLPSTLTRSMTITVFYCDGSRLPMPYT 507

  Fly   338 ----------------------------------------------------------------- 337

plant   508 VIVPKQGSIRDLITALGTACCLAEDESLLLAEVYDHKIFRYFEIPLDSLSAIKDDEHIVAYRLNQ 572

  Fly   338 -------------HGG------------------------------------------------- 340
                         |||
plant   573 IPKGSRKAKLEILHGGQERAVLDSVRGSDVKLFGTPFVTYVNTEPLSGTDIDAVISGFLSPLHKV 637

  Fly   341 ----------------------------------------------------------------V 341
                                                                            :
plant   638 HAPSKIHNGSDNGHLADATVDQASGILSSPDTEIDNASDRELSFRIFLTDERGLNIKPLQSESSI 702

  Fly   342 TPKT-------------------------------------------LIDCLERYTRAEHLGSAA 363
            :|.|                                           |..|||.:...|.||...
plant   703 SPGTVTRVLVEWNEGEHERYDSSYLSDLPEVHKTSFSAKKTRQESISLFSCLEAFLAEEPLGPDD 767

  Fly   364 KIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPV-EFDMTPFMSEKKN 427
            ...|.:||.::::.|:..|..||.::.||||||.:|..:..||.:|:.||| :.|::.::..|..
plant   768 MWFCPSCKEHRQANKKLDLWKLPDILVFHLKRFTYSRYLKNKIDTFVNFPVHDLDLSKYVKNKNG 832

  Fly   428 AYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKDT-WVKCDDHVITMASLKQVLDSEGYLLFYHK 490
            .  .:.:.||||.||.|.:..||||||.:...|. |...||..::..:..::.:|..|:|||.:
plant   833 Q--SYLYELYAVSNHYGGLGGGHYTAYAKLIDDNKWYHFDDSHVSSVNESEIRNSAAYVLFYRR 894

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	16/89 (18%)
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	109/596 (18%)
UBP9	NP_192795.3	UBP12	17..894	CDD:227847	145/777 (19%)
		DUSP	38..137	CDD:197831	5/7 (71%)
		Peptidase_C19	304..>480	CDD:271592	50/181 (28%)
		USP7_C2	505..>566	CDD:291217	0/60 (0%)
		Peptidase_C19R	<740..893	CDD:239139	50/154 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910