Protein Alignment not and USP9X

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_005272732.1
• Gene: USP9X / 8239
• HGNCID: 12632
• Length: 2575
• Species: Homo sapiens
• Alignment Length: 635
• Identity: 131/635 - (20%)
• Similarity: 215/635 - (33%)
• Gaps: 208/635 - (32%)

  Fly    15 EHSYDTFRVID-----AYFA--------ACVNRDARERKAIHCNCFECGSYGIQLYACLHCIYFG 66
            :||.|.|.::.     ||.:        ..:|.:....|.|..:....|..||:     ..|..|
Human  1375 KHSGDYFTLLRHLLNYAYNSNINVPNAEVLLNNEIDWLKRIRDDVKRTGETGIE-----ETILEG 1434

  Fly    67 CRGAHITSHL-----RSKKHNVALELSHGTLYCYACRDFIYDARSREYA--LINRKLEAKDLQKS 124
            ..|  :|..|     ..||.::..|.....|......|||:.| |..|.  :.|.:|.|:.....
Human  1435 HLG--VTKELLAFQTSEKKFHIGCEKGGANLIKELIDDFIFPA-SNVYLQYMRNGELPAEQAIPV 1496

  Fly   125 IGWVPWVPTTKETNLLLA-----NARRRL---------------------------VRPNQTIGL 157
            .|..|.:....|..:.||     |.::.:                           |.|....|.
Human  1497 CGSPPTINAGFELLVALAVGCVRNLKQIVDSLTEMYYIGTAITTCEALTEWEYLPPVGPRPPKGF 1561

  Fly   158 RGLLNLGATCFMNCIVQALVHTPLL---------------SDYFMSDRHDCGSKSSHKCLVCEVS 207
            .||.|.||||:||.::|.|...|.:               .|....::.|..|....:..|....
Human  1562 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDDVFGYP 1626

  Fly   208 RLFQEFYSGSRSP------LSLHRLLHLIWNH--AKHLAGY-------------------EQQDA 245
            :.|::..:.|::.      :.:.|.|.:|:.|  |..|..|                   ||.||
Human  1627 QQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDA 1691

  Fly   246 HEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDV 310
            .|||.:.:|.|. ..:||.. |.:                           ::.::..|......
Human  1692 LEFFNSLVDSLD-EALKALG-HPA---------------------------MLSKVLGGSFADQK 1727

  Fly   311 VCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQE 375
            :||.|.......:.|..:::|:   ..|     :.|:|.||:|.:.:.|..|....|..|....:
Human  1728 ICQGCPHRYECEESFTTLNVDI---RNH-----QNLLDSLEQYVKGDLLEGANAYHCEKCNKKVD 1784

  Fly   376 STKQFSLRTLPSVVSFHLKRFEHS-----ALIDRKISSFIQFPVEFDMTPF-------------- 421
            :.|:..::.||.|::..||||::.     |:   |.:.:.:||.|.||.|:
Human  1785 TVKRLLIKKLPPVLAIQLKRFDYDWERECAI---KFNDYFEFPRELDMEPYTVAGVAKLEGDNVN 1846

  Fly   422 ----------MSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRH------QKDTWVKCDDHVI 470
                      .||.:.| |..::.|..|:.|.|....|||.:|:..      :::.|.|.||..:
Human  1847 PESQLIQQSEQSESETA-GSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNRWYKFDDGDV 1910

  Fly   471 TMASLK----------------QVLDS--------------EGYLLFYHK 490
            |...:.                :|.|.              ..|:|||.:
Human  1911 TECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYER 1960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	15/61 (25%)
		Peptidase_C19D	158..489	CDD:239125	91/437 (21%)
USP9X	XP_005272732.1	peptidase_C19C	1560..1963	CDD:239124	93/442 (21%)
		UCH	1562..1958	CDD:278850	90/436 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910