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Protein Alignment not and USP5

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001092006.1	Gene:	USP5 / 8078	HGNCID:	12628	Length:	858	Species:	Homo sapiens

Alignment Length:	427	Identity:	85/427 - (19%)
Similarity:	150/427 - (35%)	Gaps:	120/427 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 YFGCRGA--HITSHLRSKKHNVALELSHGTL-------YCYACRDFIYDARSREYALINRKLEAK 119
            ||...|.  |...|.|...:.:|::|  ||:       |.|...|.:.|....|: |.:..::..
Human   223 YFDGSGGNNHAVEHYRETGYPLAVKL--GTITPDGADVYSYDEDDMVLDPSLAEH-LSHFGIDML 284

  Fly   120 DLQKSIGWVPWVPTTKETNLLLANARRRL------------VRPNQTIGLRGLLNLGATCFMNCI 172
            .:||         |.|....|..:..:|:            ::|....|..|:.|||.:|::|.:
Human   285 KMQK---------TDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSV 340

  Fly   173 VQALVHTP--------LLSDYFMS-------DRHDCGSKSSHKCLVCEVSRLFQEFYSGSRSP-- 220
            ||.|...|        .|...|.:       |.....:|..|..|..|.|:...|...|.|.|
Human   341 VQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQ 405

  Fly   221 ------LSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSG 279
                  ::......||.......:...||||.|||:..::::.|:|
Human   406 KEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNC------------------- 451

  Fly   280 TNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPK 344
            .:|.|.             :::|..:::..:.|.|...|..|....:.:.|.:   .....:..:
Human   452 RSSENP-------------NEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPV---PMDAALNKE 500

  Fly   345 TLIDCLERYTRAEHLGSA------AKIKCSTC--------------------KSYQESTKQFSLR 383
            .|::..|:..:||....|      |::..|:|                    ||....|.:|:
Human   501 ELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTRFA-- 563

  Fly   384 TLPSVVSFHLKRFEHSA-LIDRKISSFIQFPVEFDMT 419
            :.|..:...:|:|.... .:.:|:...|:.|.|.|::
Human   564 SFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.