DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and si:ch211-212k18.13

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_009301371.1	Gene:	si:ch211-212k18.13 / 794291	ZFINID:	ZDB-GENE-160728-93	Length:	519	Species:	Danio rerio

Alignment Length:	350	Identity:	73/350 - (20%)
Similarity:	130/350 - (37%)	Gaps:	88/350 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 GLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHKCLVCEVSRLFQEFYSGSRSPLSL 223
            ||.|.||||::|.::|.|..|....:..:..|.:...:..:  ::.::.|||::......:...:
Zfish    18 GLTNQGATCYLNAVLQCLFMTEEFREEVLRYRSEDSLEKEN--ILVQLQRLFRKLSKTVTTTEGV 80

  Fly   224 HRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSS 288
            .|.|.:     :::  :|||||.|::...|..:.....|
Zfish    81 TRSLGI-----RNV--FEQQDAVEYYRKILKTMGPLAFK-------------------------- 112

  Fly   289 HCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERY 353
                        :|.|.:.:...|..|             ..::.||.|...:.....::..:.|
Zfish   113 ------------VFEGKMINITKCGKC-------------GKEMPETNTFISILLSINVENNKMY 152

  Fly   354 -------TRAEH--LGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSF 409
                   |..||  |.....:.|..|....::.....:...|:|::.|||||:.         .:
Zfish   153 DVETGLKTFEEHSILDEDDWVYCDECDCKTKTETWTKIDEYPNVLTLHLKRFDF---------DY 208

  Fly   410 IQFPVE-----FDMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVR-HQKDTWVKCDDH 468
            :|...|     .|:...:.:|.|...   :.||||:||.|....|||.|.:: ::...|...||.
Zfish   209 MQMRYEKNECRLDVPLTLPKKDNRPS---YELYAVINHKGRYSGGHYEAIIKSYENGVWYCFDDS 270

  Fly   469 VITMASLKQVLDSE-GYLLFYHKNV 492
            .:|..|...:.:|. .|:|.|.|.|
Zfish   271 RVTETSETPLKNSSLPYMLLYRKKV 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	70/345 (20%)
si:ch211-212k18.13	XP_009301371.1	UCH	18..291	CDD:306860	70/344 (20%)
si:ch211-212k18.13	XP_009301371.1	P-loop_NTPase	305..478	CDD:328724
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910