Protein Alignment not and Usp16

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_077220.2
• Gene: Usp16 / 74112
• MGIID: 1921362
• Length: 825
• Species: Mus musculus
• Alignment Length: 827
• Identity: 159/827 - (19%)
• Similarity: 248/827 - (29%)
• Gaps: 361/827 - (43%)

  Fly     2 SETGCRHYQSYVKEHSYDTFRVIDAYFAACVN-------RDARERKAIHCNCFECGSYGIQLYAC 59
            :|..|||.:..:::.:... .:::..:..|.:       :|..|.:|      |..|    ::.|
Mouse    20 AEPVCRHLRKGLEQGNLKK-ALVNVEWNICQDCKTDNKVKDKPEEEA------EDPS----VWLC 73

  Fly    60 LHCIYFGC----RGAHITSHL---RSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLE 117
            |.|.:.||    :..|...|.   ||:.|.:.|.|.:.:::||.|.:.:      :|...||..:
Mouse    74 LKCGHQGCGRDSQEQHALKHYTTPRSEPHYLVLSLDNWSVWCYKCDEEV------KYCSSNRLGQ 132

  Fly   118 AKD-LQKSIGWVPWVPTTKET-NLLLANARRRLVRPNQ--------------------TIGLRGL 160
            ..| ::|..|.....|..|.. ::.|.|.:......|:                    .|.::||
Mouse   133 VVDYVRKQAGVRTSKPAEKNNGHIELENKKLEKESKNEQEREKSENLAKETIPMDSASQITVKGL 197

  Fly   161 LNLGATCFMNCIVQALVHTP----LLSDYFMS------DRHDCGSKSSHKC-------LVCEVSR 208
            .|||.|||.|.::|.|..||    ||.:..||      :..|.......:.       |...:|:
Mouse   198 SNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEVNLEPPGPLTLAMSQ 262

  Fly   209 LFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHE--SKS 271
            ...|.....:..::...|...:...|....||:|||:.|.....||.:...      ||:  ||.
Mouse   263 FLSEMQENKKRVVTPKELFSQVCKKATRFKGYQQQDSQELLRYLLDGMRAE------EHQRVSKG 321

  Fly   272 NSSGSGSGTNSSNSSSSH---CYGQCNCI---IDQIFTGMLQSDVVCQACNGVSTTYDPFWDISL 330
            .....|:.|...:....:   .|.:...|   :|:||.|.|.|.::|..|..||..::.|.|:||
Mouse   322 ILKAFGNSTEKLDEEVKNKVKDYEKKKAIPSFVDRIFGGELTSTIMCDECRTVSLVHESFLDLSL 386

  Fly   331 -----------------------------------------DL---------------------- 332
                                                     ||
Mouse   387 PVLDDQSGKKSINDKNVKMTMEEEDKDSEEEKDDSYMKSRSDLPSGTSKHLQKKAKKQAKKQAKN 451

  Fly   333 -----------------------------------GET-----TTHGG----------------- 340
                                               ||.     :|||.
Mouse   452 QRRQQKIQERFLHFNELCATDYTEDNEREADTALAGEVEVDTDSTHGSQEEATQIELSVNQKDLD 516

  Fly   341 --------------------------------VTP---------------------------KTL 346
                                            |||                           |.|
Mouse   517 GQESMIERTPDVQESPEDLGVKSANTESDLGIVTPAPECPRDFNGAFLEERTSGELDIINGLKNL 581

  Fly   347 -----ID------------------------------------------------CLERYTRAEH 358
                 :|                                                ||.::||.|.
Mouse   582 NLNAAVDPDEINIEIPNDSHSAPKVYEVMNEDPETAFCTLANREAFSTDECSIQHCLYQFTRNEK 646

  Fly   359 LGSAAKIKCSTCKS-----------------YQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKI 406
            |..|.|:.|..|..                 |..:.||..:...|.|::.|||||:.:....||:
Mouse   647 LQDANKLLCEVCSRRQCNGPKANIKGDRRHVYTNAKKQMLVSLAPPVLTLHLKRFQQAGFNLRKV 711

  Fly   407 SSFIQFPVEFDMTPFMSEK-KNAYGD---FRFSLYAVVNHVGTIDTGHYTAYVRHQ--------- 458
            :..|:||...|:.||.:.| ||...:   ..:|||.||.|.||:.:||||||.:.:
Mouse   712 NKHIKFPEILDLAPFCTLKCKNVAEESTRVLYSLYGVVEHSGTMRSGHYTAYAKERTASCHLSNL 776

  Fly   459 ---------------KDTWVKCDDHVITMASLKQVLDSEGYLLFYHK 490
                           |..|....|..:....:.:||:|:.|||||.:
Mouse   777 VLHGDIPQDCEMESTKGQWFHISDTHVQAVPITKVLNSQAYLLFYER 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	17/63 (27%)
		Peptidase_C19D	158..489	CDD:239125	121/632 (19%)
Usp16	NP_077220.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		159/827 (19%)
		zf-UBP	48..122	CDD:366940	21/83 (25%)
		UBP12	<135..823	CDD:227847	131/693 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	164..184		1/19 (5%)
		Peptidase_C19K	196..>401	CDD:239132	53/210 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..456		2/62 (3%)
		Peptidase_C19K	<624..822	CDD:239132	55/197 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910