DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and Usp36

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_036012906.1	Gene:	Usp36 / 72344	MGIID:	1919594	Length:	1127	Species:	Mus musculus

Alignment Length:	362	Identity:	104/362 - (28%)
Similarity:	183/362 - (50%)	Gaps:	57/362 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 ARRRLVRPNQTIGLR---------GLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSH 199
            |.::::.|.:.:.||         ||.|||.|||:|..:|.|.:||.|::|.:|..|   ::|.|
Mouse   128 APQKVLFPVERLSLRWERVFRVGAGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEH---ARSCH 189

  Fly   200 K---CLVCEV-SRLFQEFYSGSRS--PLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHR 258
            :   |::|.: :.:.|.|.:...:  |:|..|.|..|   |:|.....|:|||||...|:|.:.:
Mouse   190 QGGFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKI---ARHFRFGNQEDAHEFLRYTIDAMQK 251

  Fly   259 HCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYD 323
            .|:...|:.:.::                     |...::.|||.|.|:|.|.|..|..||.|||
Mouse   252 ACLNGYAKLDRQT---------------------QATTLVHQIFGGYLRSRVKCSVCKSVSDTYD 295

  Fly   324 PFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSV 388
            |:.||:|::.:..        .::..||.:.:::.|.......|:.||....::|:|::....:|
Mouse   296 PYLDIALEIRQAA--------NIVRALELFVKSDVLSGENAYMCAKCKKKVPASKRFTIHRTSNV 352

  Fly   389 VSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAYGD-FRFSLYAVVNHVG-TIDTGHY 451
            ::..||||.:.:  ..||:..:.:|...::.|:||:..   || ..:.||||:.|.| :...|||
Mouse   353 LTLSLKRFANFS--GGKITKDVGYPEFLNIRPYMSQSS---GDPVMYGLYAVLVHSGYSCHAGHY 412

  Fly   452 TAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 488
            ..||:.....|.:.:|.::..:::|.||:.:.|:|||
Mouse   413 YCYVKASNGQWYQMNDSLVHSSNVKVVLNQQAYVLFY 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	101/348 (29%)
Usp36	XP_036012906.1	Peptidase_C19E	150..450	CDD:239126	100/340 (29%)
Usp36	XP_036012906.1	PHA03247	<508..1018	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D929408at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920