Protein Alignment not and Usp19

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_006511895.1
• Gene: Usp19 / 71472
• MGIID: 1918722
• Length: 1361
• Species: Mus musculus
• Alignment Length: 731
• Identity: 118/731 - (16%)
• Similarity: 174/731 - (23%)
• Gaps: 408/731 - (55%)

  Fly   363 GLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHD--------------CGSKSSHKCLVCEV 413
            |..||:|||.|||||.::|:|.:|..|.|:|    ||              .|.:     |....
Mouse   538 GFTGLVNLGNTCFMNSVIQSLSNTRELRDFF----HDRSFEAEINYNNPLGTGGR-----LAIGF 593

  Fly   414 SRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKS 478
            :.|.:..:.|:.......:|..::.:.|....||.|.||.||....||.||....:.:.:..:::
Mouse   594 AVLLRALWKGTHQAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTET 658

  Fly   479 -NSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPF---------- 532
             :|.|......:..:...|.....:.|:| :|.|..:|.:||..|..||.|:|||
Mouse   659 VDSDGRPDEVVAEEAWQRHKMRNDSFIVD-LFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQK 722

  Fly   533 ----------------------------------------------------------------- 532
                                                                             
Mouse   723 QKVLPIFYFAREPHSKPIKFLVSVSKENSSASEVLDSLSQSVHVKPENLRLAEVIKNRFHRVFLP 787

  Fly   533 ----------------------------------------------------------------- 532
                                                                             
Mouse   788 SHSLDAVSPTDVLLCFELLSPELAKERVVVLEVQQRPQVPSIPISKCAACQRKQQSEEEKLKRCT 852

  Fly   533 ----------------W------------------------------------------------ 533
                            |
Mouse   853 RCYRVGYCNQFCQKTHWPDHKGLCRPENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPP 917

  Fly   534 --------------------DISLDLGET------------------------------------ 542
                                ..||:.|::
Mouse   918 FQPGRMALESQSPGCTTLLSTSSLEAGDSEREPIQPSELQLVTPVAEGDTGAHRVWPPADRGPVP 982

  Fly   543 -------------------------------------------TTH------------------- 545
                                                       .||
Mouse   983 STSGLSSEMLASGPIEGCPLLAGERVSRPEAAVPGYQHSSESVNTHTPQFFIYKIDASNREQRLE 1047

  Fly   546 -GGVTPK-----------------------------------------------TLIDCLERYTR 562
             .|.||.                                               ||..||..:||
Mouse  1048 DKGETPLELGDDCSLALVWRNNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTR 1112

  Fly   563 AEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDR-KISSFIQFPV-EFDM 625
            .|.|.......|..||.::|::||..|..||:|:...||||...:.|.| ||:..::||| ..|:
Mouse  1113 PEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDL 1177

  Fly   626 TPF-MSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKDT--------WVKCDDHVITMAS 681
            :.| :.:|:.....  :.||||:||.|.:..|||||..|...|.        |...||..:|...
Mouse  1178 SKFCIGQKEEQLPS--YDLYAVINHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVD 1240

  Fly   682 LKQVLDSEGYLLFYHK 697
            ..||:....|:|||.:
Mouse  1241 ESQVVTRYAYVLFYRR 1256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464
		Peptidase_C19D	365..696	CDD:239125	116/726 (16%)
Usp19	XP_006511895.1	p23_like	58..140	CDD:107220
		p23_CS_SGT1_like	329..425	CDD:107223
		USP19_linker	416..538	CDD:465191	118/731 (16%)
		UBP12	<536..1258	CDD:227847	118/731 (16%)