Protein Alignment not and usp11

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_002663119.3
• Gene: usp11 / 568334
• ZFINID: ZDB-GENE-081104-421
• Length: 990
• Species: Danio rerio
• Alignment Length: 898
• Identity: 144/898 - (16%)
• Similarity: 236/898 - (26%)
• Gaps: 472/898 - (52%)

  Fly    19 DTFRVIDAYFAACVNRDARERKAIHC-NCFECGSYGIQLYACLHCIYFGCRGAHITSHLRSKKHN 82
            :.:|.:.:::....|:...|||.:.. :..:...|.:::|.||            :|:|.|   .
Zfish    96 EAWRKLLSWYDMMDNQPPLERKVVDLPSTVKVEVYPVEIYLCL------------SSNLES---T 145

  Fly    83 VALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRR 147
            |..:.|..        |.|:....:    |.:..:..:..:|..|:..|.|:.|          |
Zfish   146 VTAQFSRA--------DKIHAIHQK----IRQHFDVSETAESRLWMRSVDTSSE----------R 188

  Fly   148 LVRPNQTI-------------------------------------------GLRGLLNLGATCFM 169
            |...|.|:                                           |:.||.|||.||||
Zfish   189 LRNLNMTVLDSCLSSGMTVIMEIRNADGTWPTSRPQIMRNSADEDSYRGPPGVCGLTNLGNTCFM 253

  Fly   170 NCIVQALVHTPLLSDYFMSD--------RHDCGSKSSHKCLVCEV-SRLFQEFYSGSRSPLSLHR 225
            |..:|.|.:||.|::||:.:        .:..|.|..    :.|. :.:.::.:||....:....
Zfish   254 NSALQCLSNTPPLTEYFLKNLYLEELNFSNPLGMKGE----IAEAYADVIKQMWSGRHYSVVPRV 314

  Fly   226 LLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKA-KAEHESKSNSSGSGSGTNSSNSSSSH 289
            ....:.:.|....||:|.|:.|.....||.||....:. |.|:....::.|......:..:..:|
Zfish   315 FKTKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYIELRDADGRPDQEVAEEAWRNH 379

  Fly   290 CYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPF-----------------WDISLD------ 331
            .....:.|:| .|.|:.:|.:||..||.||.|:|||                 :.:|||
Zfish   380 LRRNDSVIVD-TFHGLFKSTLVCPECNKVSVTFDPFCYLSVPLPVSKERVMEVFYVSLDPTAKPT 443

  Fly   332 ------------------LGETTTHGGVTP----------------------------------- 343
                              |.:.|   ||.|
Zfish   444 QYRLIVPKAGRVLDLCTALSQAT---GVPPNQMTVTDVFNHRFYRIYQSDESLSCILDRDDIFVY 505

  Fly   344 ------------------------------------------------------------KTLID 348
                                                                        :.|::
Zfish   506 QLSSGCVDEDSDEVVLSIYMRERSHYRDYGSGSNSYGTSLFGHPLRMSVPRAHCTPEHLYQLLLE 570

  Fly   349 CLERYTR-----------------------------------AEHLGSAAK-------------- 364
            .|.||.|                                   :|..||:.|
Zfish   571 RLARYVRPLDPSEEVEEEEEDDEEELYKAQTNGVSDDEGEEDSEEAGSSKKEEEPRASNEVNEQN 635

  Fly   365 ----------------------------------------------------------------- 364
                                                                             
Zfish   636 NGQSEASPSSEGEERAEEEESSSEQERGSSTEEGQSACGSTDTTDGDQSAGAEPSGKEEDEDEEE 700

  Fly   365 ----------------------------------------------------------------- 364
                                                                             
Zfish   701 EDGEEAASCTPANKRHPGRRRYTERRKKALFTIQAVNSNGTTERGMAEAGGSISFSSQPYIAIDW 765

  Fly   365 -----------------IK-----------------------------------CSTCKSYQEST 377
                             ||                                   |.|||.:|.:|
Zfish   766 DPDMKKKYYNENEAEKYIKHQSMDVPHQQTTVQLQECIELFTTVETLEEENPWYCPTCKRHQLAT 830

  Fly   378 KQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPV-EFDMTPFMSEK--KNAYGDFRFSLYAV 439
            |:..|.:||.|:..|||||.::.....|:.:.::||: :.|.:.|:.:|  .:......:.|.:|
Zfish   831 KKLDLWSLPEVLIIHLKRFSYTKYSREKLDTIVEFPLRDLDFSGFLLKKTVNSTEPPCPYDLISV 895

  Fly   440 VNHVGTIDTGHYTAYVRHQKDT--WVKCDDHVITMASLKQVLDSEGYLLFYHK 490
            .||.|.:..||||:|.|: ||.  |...||..:|.|..:|::.|..|||||.:
Zfish   896 SNHYGGLRDGHYTSYARN-KDNGQWYYFDDSKVTYAREEQIVTSAAYLLFYQR 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	11/56 (20%)
		Peptidase_C19D	158..489	CDD:239125	116/712 (16%)
usp11	XP_002663119.3	UBP12	15..947	CDD:227847	144/896 (16%)
		DUSP	34..119	CDD:283896	5/22 (23%)
		Ubiquitin_3	133..219	CDD:291502	20/122 (16%)
		Peptidase_C19	242..>419	CDD:271592	51/181 (28%)
		USP7_C2	413..>504	CDD:291217	10/93 (11%)
		Peptidase_C19R	<793..946	CDD:239139	46/153 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940