DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and usp12a

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001077025.1	Gene:	usp12a / 565736	ZFINID:	ZDB-GENE-060228-3	Length:	371	Species:	Danio rerio

Alignment Length:	383	Identity:	103/383 - (26%)
Similarity:	161/383 - (42%)	Gaps:	108/383 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 GLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHKCLVCEVSRLFQEFYSGSRSP--- 220
            ||:|.|.||:.|.::|||        ||                 |   |.|:|.....||.
Zfish    40 GLVNFGNTCYCNSVLQAL--------YF-----------------C---RPFREKILAYRSQPRR 76

  Fly   221 -----LSLHRLLHLIWNHAKHLA-------------------GYEQQDAHEFFIATL----DVLH 257
                 ..|..|.|.|.|..:.:.                   .|.|||||||....|    |:|.
Zfish    77 KENLLTCLADLFHSIANQKRKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADLLQ 141

  Fly   258 RHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTY 322
            .   :.|.:.::...::|:....|::::..|..:      :.:||.|.|.::..|..|..:|:..
Zfish   142 E---ERKQDKQNGKLANGTLDSQNNNSTPPSTTW------VHEIFQGTLTNETRCLTCETISSKD 197

  Fly   323 DPFWDISLDLGETT--THGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTL 385
            :.|.|:|:|:.:.|  ||          ||..::..|.|.|..|..|..|:|.||:.|:..::.|
Zfish   198 EDFLDLSVDVEQNTSITH----------CLRGFSNTETLCSEYKYYCEECRSKQEAHKRMRVKKL 252

  Fly   386 PSVVSFHLKRFEHSALIDR--KISSFIQFPVEFDMTPFMSEKKNAYGDFR-----FSLYAVVNHV 443
            |.:::.|||||::...:.|  |:|..:.||:|..:.       |..||..     :.|.|||.|.
Zfish   253 PMILALHLKRFKYMEQLQRYTKLSYRVVFPLELRLF-------NTSGDATNPERLYDLVAVVVHC 310

  Fly   444 GT-IDTGHYTAYVRHQKDTWVKCDDHVITMASLKQV-----LDSE-------GYLLFY 488
            |: .:.|||.|.|: ..|.|:..||.::.....:.:     |.||       ||:|||
Zfish   311 GSGPNRGHYIAIVK-SHDFWLLFDDDIVEKIDAQAIEEFYGLTSEISKNSESGYILFY 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	103/383 (27%)
usp12a	NP_001077025.1	UCH	38..367	CDD:278850	101/381 (27%)
		Peptidase_C19G	40..368	CDD:239128	103/383 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	148..169		2/20 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910