Protein Alignment not and usp33

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001016228.1
• Gene: usp33 / 548982
• XenbaseID: XB-GENE-1016674
• Length: 892
• Species: Xenopus tropicalis
• Alignment Length: 672
• Identity: 149/672 - (22%)
• Similarity: 230/672 - (34%)
• Gaps: 252/672 - (37%)

  Fly    40 KAIHCNCFECGSYGIQLYACLH--CIYFGCRGAHI---TSHLRSKKHNVALELSHGTLYCYACRD 99
            |..|.:|.:|...|..|:|||.  |.|.||..:|:   |.|.:..||.:.:.|:...::||.|..
 Frog    24 KKSHGSCQDCRVRGPNLWACLENGCSYVGCGESHVDHSTLHSQDTKHCLTVNLTTLRVWCYTCSK 88

  Fly   100 FIYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPN-----------Q 153
            .::..|.......:.||:....|:|          |.::.|.......:|..|           :
 Frog    89 EVFLDRKLSTQPTSAKLQDSHTQES----------KMSSSLTLKIPAAVVSENLDIELEEEDELK 143

  Fly   154 TIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCG--SKSSHKCLVCEVSRLFQEFYSG 216
            |.||.||.|:|.||:||..:|||.:.|.|:.||:    |||  :::..|..:|:
 Frog   144 TRGLTGLKNIGNTCYMNAALQALSNCPPLTHYFL----DCGGLARTDKKPALCK----------- 193

  Fly   217 SRSPLSLHRLLHLIWNHAK------------------HLAGYEQQDAHEFFIATLDVLHRHCVKA 263
                 |..:|:..||:..:                  ...||.||||.||....:||||....:.
 Frog   194 -----SYQKLMSDIWHKNRPGFVIPTNLFQGIKSVNPTFRGYSQQDAQEFLRCLMDVLHEELKEQ 253

  Fly   264 --------------------KAEHESKSNSSGSGSGTNSSNSSS--------------------- 287
                                |::.::..:|..|||.::.:.|.|
 Frog   254 IVEVEEDAQTGIVEENLDEDKSQSDNDFHSCDSGSSSDHAESESRKLSEELTESTMLIHEDQKDV 318

  Fly   288 -----------------------------------SHCY-------------------------- 291
                                               |.|.
 Frog   319 EICKTWQKEKKFSNNLNQNHFLQDFEKNIQSTIEESECLKQETVKVQIQSKAADFTAEVNMNDLP 383

  Fly   292 ---------------------------------GQC----------NCIIDQIFTGMLQSDVVCQ 313
                                             |.|          :.:|..||.|.:.|.|.|.
 Frog   384 TSQTPLLNEGATTHLSSSPPKPGAVWTGHKKVPGLCPAKKRKQKKYHSVIADIFDGTIVSSVQCL 448

  Fly   314 ACNGVSTTYDPFWDISL------DLGE--TTTHGGVTPK-------------------------- 344
            .|:.||.|.:.|.|:||      ||.:  :::|.....|
 Frog   449 TCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHQSSLVKAGSCGEAYAPQGWIAFFLEYFKSWFW 513

  Fly   345 ----TLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRK 405
                ||.|||..:...:.|.......|..||..:...|...::..|.::..|||||.|..:...|
 Frog   514 GPTVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRFRHELMFSTK 578

  Fly   406 ISSFIQFPVE-FDMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQ-KDTWVKCDDH 468
            |.:.:.||:| .|:.||:: |.:......:.|.:|:.|.||..:|||.||.|:. .:.|.:.||.
 Frog   579 IGTHVSFPLEGLDLQPFLA-KDSPSQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQ 642

  Fly   469 VITMASLKQVLDSEGYLLFYHK 490
            .:|..|...|.::|.|:|||.|
 Frog   643 SVTEVSEATVQNAEAYVLFYRK 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	20/61 (33%)
		Peptidase_C19D	158..489	CDD:239125	113/535 (21%)
usp33	NP_001016228.1	zf-UBP	30..90	CDD:280334	20/59 (34%)
		UCH	147..662	CDD:278850	113/535 (21%)
		Peptidase_C19	148..>178	CDD:271592	15/33 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..311		7/42 (17%)
		Peptidase_C19R	430..663	CDD:239139	66/233 (28%)
		DUSP	684..764	CDD:197831
		DUSP	790..871	CDD:197831

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910