DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and AgaP_AGAP001052

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_003437188.1	Gene:	AgaP_AGAP001052 / 4575976	VectorBaseID:	AGAP001052	Length:	724	Species:	Anopheles gambiae

Alignment Length:	372	Identity:	108/372 - (29%)
Similarity:	183/372 - (49%)	Gaps:	47/372 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 RLVRP---------------NQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYF----MSDRHD 192
            ||::|               |...||.||.|:|.|||||.::|.|.||..|:.:.    .|:|
Mosquito   371 RLIKPSLNYERCTEVNDSLRNTREGLCGLWNIGNTCFMNSMIQCLSHTRELTSFLRGQSSSER-- 433

  Fly   193 CGSKSSHKCLVCEVSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLH 257
             |:...| .::.|.::|.:..:||::..::...|.:...:..:..:|..||||.||....||.||
Mosquito   434 -GTSKDH-LILAEYTKLIKNMWSGTQRSINPSDLKYAFSSKHRMYSGSAQQDAQEFLRFFLDSLH 496

  Fly   258 RHCVKAKAEHESKSNSSGSGSGTNSSNSSSS----HCYGQC-NCIIDQIFTGMLQSDVVCQACNG 317
             ..:.|..:.:..|...     .|.:|...:    ..|.:. |.:|..:|.|.|:|.:.|..||.
Mosquito   497 -GALNAAIKRDPLSEID-----DNMNNKDKADMLWEWYSKAENSMIKDLFVGQLRSTLKCTFCNM 555

  Fly   318 VSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSL 382
            .||.:|||||:||.|..:::.     ..|.:|||.:.:.|.:....:..||.|.:.::.||:.::
Mosquito   556 ESTMFDPFWDLSLPLPSSSSR-----CKLENCLEMFIKEEIMDGIDQPTCSNCDTRRKCTKRLTI 615

  Fly   383 RTLPSVVSFHLKRFEHSALIDRKISSFIQFPVE---FDMTPFMSEKKNAYGDFRFSLYAVVNHVG 444
            ...|..:..|||||..:..  .|:::.::||.:   .::.|:.||  :..|...:|||.:.||:|
Mosquito   616 ERFPRYLVIHLKRFSEARW--SKLTNIVEFPTKNRALNLQPYASE--DISGPIYYSLYGISNHMG 676

  Fly   445 TIDTGHYTAYVRH-QKDTWVKCDDHVITMASLKQVLDSEGYLLFYHK 490
            :...|||.|..:| |...|.:.:|:.:|.|..:.::.|..|:|||.:
Mosquito   677 STAGGHYVAVCKHPQTQQWNEFNDNYVTEAFERNLVTSNAYVLFYER 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	101/343 (29%)
AgaP_AGAP001052	XP_003437188.1	UCH	396..721	CDD:278850	101/343 (29%)
AgaP_AGAP001052	XP_003437188.1	Peptidase_C19R	398..722	CDD:239139	101/342 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910