Protein Alignment not and usp4

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_002662556.2
• Gene: usp4 / 449927
• ZFINID: ZDB-GENE-041008-187
• Length: 1009
• Species: Danio rerio
• Alignment Length: 678
• Identity: 114/678 - (16%)
• Similarity: 185/678 - (27%)
• Gaps: 357/678 - (52%)

  Fly   363 GLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHKCLVCEVSR------------ 415
            ||.||.|||.|||||..:|.|.:||.|::||:.||::           .|::|
Zfish   317 GLCGLSNLGNTCFMNSALQCLSNTPPLTEYFLEDRYE-----------AEINRENPLGMRGEIAE 370

  Fly   416 ----LFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAE-HE 475
                |.::.:....|.::.......:...|...:||:|||:.|.....||.||....:.|.: :.
Zfish   371 AYADLVKQMWLSRSSYVAPRTFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYL 435

  Fly   476 SKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDL- 539
            :..::.|......:..:.::|.....:.|:| ||.|:.:|.:||..|:.||.|:|||..::|.|
Zfish   436 ALRDAEGRPDEIVAKEAWANHRLRNDSIIVD-IFHGLFKSTLVCPECSKVSVTFDPFCYLTLPLP 499

  Fly   540 ----------------------------------------------------------------- 539
                                                                             
Zfish   500 MKKDRTMEVYLVRTDPQFRAMQFRVVVPKMGAVADLCSALAKLSGVPSENMVVADVYNHRFHKIY 564

  Fly   540 ----------------------------------------------------------------- 539
                                                                             
Zfish   565 KRDDGLNQIMEKDDIFVYEVLEEDSERMNLPVYFRERHAKHSGGSSGTMLFGQPLLITVPRLNLT 629

  Fly   540 ----------------------------------------------------------------- 539
                                                                             
Zfish   630 VDTLYERVLERIGRYVKRSQGTITESRASASATSSSSSQSPECLASVSSHGTGLSGCSSPVSDGA 694

  Fly   540 ----------------------------------------------GE----------------- 541
                                                          ||
Zfish   695 SCSAGSNGSNHSGTCNGPNGVCDGDEEAMDHQESPEPENSHSDTVDGEEDSEPENGPNSSGGKSF 759

  Fly   542 -------------------------------TTTHGGV--------------------------- 548
                                           .|||..|
Zfish   760 NSRPKLFSFSMVNSYGTANISSLPFDGNLLKLTTHSTVAIDWDSDTKRLCYDDQEAEAYDKHESM 824

  Fly   549 -------TPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHS 606
                   |...|.:|:|.:|..|.||......|.|||.:|::||:|.|.:||.::..|||||.::
Zfish   825 LHAQKKKTTVALRECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPRILVVHLKRFSYN 889

  Fly   607 ALIDRKISSFIQFPV-EFDMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKD-TW 669
            .....|:.:.:.||: :.:|:.|:.:.|  ...:.:.|.||.||.|.:..||||||.:::.| .|
Zfish   890 RCWRDKLDTVVDFPIRDLNMSEFVCDPK--ADPYIYDLIAVSNHYGGMGGGHYTAYGKNKADGKW 952

  Fly   670 VKCDDHVITMASLKQVLDSEGYLLFYHK 697
            ...||..::.|:..|::....|:|||.:
Zfish   953 YYFDDSSVSAATEDQIVTKAAYVLFYQR 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464
		Peptidase_C19D	365..696	CDD:239125	111/673 (16%)
usp4	XP_002662556.2	UBP12	8..981	CDD:227847	114/678 (17%)