Protein Alignment not and usp3

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_012821863.1
• Gene: usp3 / 448475
• XenbaseID: XB-GENE-962759
• Length: 522
• Species: Xenopus tropicalis
• Alignment Length: 487
• Identity: 149/487 - (30%)
• Similarity: 233/487 - (47%)
• Gaps: 62/487 - (12%)

  Fly   251 CNCFECGSYGIQLYACLHCIYFGCRGAHITSHLRSKK-------HNVALELSHGTLYCYACRDFI 308
            |:...||.| :..:|..|   :....|.:..|.|.:|       |.|.::.|..:.|||.|.||:
 Frog    44 CSSVHCGRY-VNGHAKKH---YEDAQAPLNCHKRQEKTDKDRMQHTVCMDCSSYSTYCYRCDDFV 104

  Fly   309 YDARSREYALINRKLE-AKDLQKSIGWVPWVPTTKETN-----LLLANARRRLVRPN-QTIGL-- 364
              ....:..|:.:..| .::|:.|       ..|.|.:     |..|:..::|::.| .|..|
 Frog   105 --VNDTKLCLVQKVREHLQNLENS-------AFTAERHRKRKFLESASLSKKLLKVNGSTTALCA 160

  Fly   365 RGLLNLGATCFMNCIVQALVHTPLLSDYF-------MSDRHDCGSKSSHK--------CLVCEVS 414
            .||.|||.|||||.|:|:|.:......||       :.:....|.::.|.        .||.|..
 Frog   161 TGLRNLGNTCFMNAILQSLSNIQQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDVNVSLVEEFR 225

  Fly   415 RLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSN 479
            :.....:.|:::..|...|.:::|....:..||:|||||||....||.||   ::.:.|.:..|:
 Frog   226 KTLCALWQGNQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLH---LELQGEFDGSSH 287

  Fly   480 SSGSGSGTNSSNSSSSH-CYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGE-- 541
            |..|.:  |.|.|:|:. |....:.::..:|.|:||::|.|..|...|..:|||.|:|||:..
 Frog   288 SVLSQA--NCSRSASNKCCINGASTVVTSVFGGVLQNEVNCLICGTESRKFDPFLDLSLDIPSQF 350

  Fly   542 -----TTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLK 601
                 .....|.| .||.|||..:|..|.|.......|..||..|:|||:|.::.||.|:..|||
 Frog   351 RNKRCKNQENGPT-CTLRDCLRSFTDLEELDETELYTCLKCKKKQKSTKKFWIQKLPKVLCLHLK 414

  Fly   602 RFEHSALIDRKISSFIQFPVE-FDMTPFMSEKKNAYGD-FRFSLYAVVNHVGT-IDTGHYTAYVR 663
            ||..:|.:..|:.:::.||:. .||..|:.|.:|...: ..:.|.|||.|.|: :.:||||||..
 Frog   415 RFHWTAYLRNKVDTYVDFPLRGLDMKSFLLEPENIGPESCLYDLAAVVVHHGSGVGSGHYTAYAT 479

  Fly   664 HQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 695
            | |..|...:|..:|:...:.|..::.|:|||
 Frog   480 H-KGRWFHFNDSTVTLTEEETVAKAKAYILFY 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464	18/63 (29%)
		Peptidase_C19D	365..696	CDD:239125	118/357 (33%)
usp3	XP_012821863.1	zf-UBP	29..107	CDD:460464	19/68 (28%)
		UCH	161..510	CDD:425685	116/355 (33%)