Protein Alignment not and Usp1

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_651687.3
• Gene: Usp1 / 43462
• FlyBaseID: FBgn0028476
• Length: 1078
• Species: Drosophila melanogaster
• Alignment Length: 760
• Identity: 138/760 - (18%)
• Similarity: 235/760 - (30%)
• Gaps: 304/760 - (40%)

  Fly   120 VAAAAATTTNAGRFITADLIKTVNSDKQRDRVAKGHRDAKNPLDATKHLRLSDCLRTVQ--KLAI 182
            |.|.:.|.|.:..:...:..|:    :..:|:    .:|:.|....|..|....|:..:  ||..
  Fly   142 VQAPSPTPTESTEYTPPEQFKS----EFWNRI----EEAQEPKPVGKKRRTPGGLKRTRGNKLLK 198

  Fly   183 ELE-----------SADAGSDASAQANASADASSAVMSETGC---RHYQSYVKEHSYDTFRVIDA 233
            |||           :|.|..:|:.::.|:...||...:.|..   |.:|:..:|.     ||.:.
  Fly   199 ELEIQSPETAAAIAAAQAELNAAGKSGAAGARSSRKRTNTMSLYDRRFQTTTEER-----RVANG 258

  Fly   234 YFAACVNRDARERKAIHCNCFECGSYGIQLYACLHCIYFGCRGAHITSHLRSKKHNVALELSH-- 296
            |.....      |.....:..|..|...|.:.     |:|..|....:...:..:..|..|:|
  Fly   259 YGGNAA------RSVTGSSSNEIESQEPQSHQ-----YYGPNGGSNAAGAGAGLNGSAAALNHAP 312

  Fly   297 --GTL-----YCYACRDFIYDARSREYALIN---------------------------RKLEAKD 327
              |||     .|| ....:|..|...:.|.|                           :.:.|..
  Fly   313 SMGTLCNIGNSCY-LNSVVYTLRFAPHFLHNLHHLIQDLNVVQQTIVRQQTARSASLGKNVSAAQ 376

  Fly   328 LQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDY 392
            |:.:..|     ::|:    ||.:      .:|..|..|.:|.|
  Fly   377 LEHARSW-----SSKD----LATS------TDQYSGQNGGVNSG--------------------- 405

  Fly   393 FMSDRHDCGSKSSHKCLVCEVSRLFQEFY----SGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAH 453
               :.....|||:|:.:..::..|:...:    :.|..|.....|||.|.:......|.:|||||
  Fly   406 ---NGGSGSSKSTHQSVTEKLHELYNNLHGNEMADSTEPYHADTLLHAIQDVNATFEGNQQQDAH 467

  Fly   454 EFFIATLDVL---HRHCVKA--------------------KAEHESKSNSSGS------------ 483
            ||.:..|:.:   ::..:||                    ..|.:.:::|:.|
  Fly   468 EFLMCVLNCIRETNQSLIKAIGECPEVIANGYIANPDEVDTGEGQDRTDSTASQNLNAGNGSLAT 532

  Fly   484 --------------------------------------------GSGT----------------- 487
                                                        |:||
  Fly   533 SQTTTTKTSFFSRKSKRKDEVKPSKSTRVQSPLKENSPTAGGITGAGTAHATANSLFYLNTVDLS 597

  Fly   488 ---NSSNSSSSHCYG------------------------QCNCIIDQI----------------- 508
               ::|.|:|:...|                        ....:.|::
  Fly   598 GASSTSGSASTSASGVVSTSAALPTPPQATKYSSDDEMNSATVLKDKMRLEERIRELNLNFFSSD 662

  Fly   509 FTGMLQSDVVCQACNGVSTTYDPFWDISL----------DLGETTTHGGVTPKTLI--DCL-ERY 560
            |.|::.....|.:|..::.......|||:          ||.:       .|.|.|  .|: :.|
  Fly   663 FEGIVVLTTKCLSCETITRQKQGMLDISVPVPISGYDNADLQD-------KPSTYIQNSCITKEY 720

  Fly   561 TRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDM 625
            .|.|:     |..|:.|..|.|:.:..|...||.::...|.||....   .|:|:::  |..|.:
  Fly   721 FRGEN-----KYSCNQCTGYTEAIRSISYEVLPRLLVIQLNRFSGGM---EKVSTYV--PTTFTL 775

  Fly   626 TPFMS--------EKKNAYGDFRFSLYAVVNHVG-TIDTGHYTAY 661
            ..|.:        .|.:.|     .||:|:.||| |:..|||.||
  Fly   776 PCFCATCCELGEGNKLHVY-----KLYSVITHVGATLTVGHYIAY 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464	14/65 (22%)
		Peptidase_C19D	365..696	CDD:239125	82/463 (18%)
Usp1	NP_651687.3	Peptidase_C19	308..819	CDD:470612	101/570 (18%)