Protein Alignment not and usp44

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_956551.1
• Gene: usp44 / 393227
• ZFINID: ZDB-GENE-040426-774
• Length: 695
• Species: Danio rerio
• Alignment Length: 678
• Identity: 155/678 - (22%)
• Similarity: 235/678 - (34%)
• Gaps: 255/678 - (37%)

  Fly    45 NCFECGSYGIQLYACLHCIYFGCR---GAHITSHLRSKKHNVALELSHGTLYCYACRDFIYD--- 103
            :|.:|.:.. .::|||.|.:..|.   ..|...|.:.:.|.:|||::...:|||.|.|::.:
Zfish    25 HCVDCNTTE-SVWACLSCSHVACGRYIEEHALQHFKEQHHPLALEVNELYVYCYLCDDYVLNDNA 88

  Fly   104 ----------------------ARS-----------------------------------REYAL 111
                                  .||                                   |..||
Zfish    89 TGDLKLLRSTLSAIKSQCYEVTTRSGRTLRSSSANGDQLSPSTQELQLRDEDRMFTALWHRRRAL 153

  Fly   112 I----------------------------NRKLEAKD--------LQKSIGWVPWVP-------- 132
            |                            .||.||::        |::.:...|  |
Zfish   154 IGRLFRLWFAQTERGKKRLEEERQQEEEEERKREARERRRQLKRQLKEELESAP--PRKSHRIRR 216

  Fly   133 -TTKETNLLLANA--------RRRLV--------------------------------------- 149
             :.|.|::..|.|        |||..
Zfish   217 QSLKATSVKPARAPAKSTKSVRRRSAPARVSTPTPRTPRERTPQQRPRPQAKAKRPQAPPSKTGD 281

  Fly   150 -----RPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDC---------------- 193
                 ||..|.|:.||.|||.||:||.|:|.|.|..:..:.|:  |.|.
Zfish   282 SPVKRRPTVTPGVTGLRNLGNTCYMNSILQVLSHLHVFRECFL--RLDLNQALELLASAVSRKLG 344

  Fly   194 --------------GS--------------------KSSHKCLVCEVSRLFQEFYSGSRSPLSLH 224
                          ||                    .|.|..|..|:..||...:||..:.:|..
Zfish   345 LSAQRVIQPKGLNQGSGLSGGASRSRNMELIQPKEPSSKHISLCHELHTLFPVMWSGKWALVSPF 409

  Fly   225 RLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSH 289
            .:||.:|.......||.||||.||....||         |.:||.:...:.:.:   :..::...
Zfish   410 AMLHSVWQLIPAFRGYAQQDAQEFLCELLD---------KVQHELERTRTLTPA---TVPANQRR 462

  Fly   290 CYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGE----TTTHGGVTPKTLIDCL 350
            ...|...:::.||.|.|.|.|.|.||:..|.|.:||||:||:..|    .:......|..|.:.|
Zfish   463 LIKQVLSVVNTIFHGQLLSQVRCLACDHRSNTIEPFWDLSLEFPERYHSNSKDAAQVPCGLTEML 527

  Fly   351 ERYTRAEHLGSAAKIKCSTCKSYQ-----------ESTKQFSLRTLPSVVSFHLKRFEHSALIDR 404
            .::|..|.| ..|...|..|.:.:           |:.||..:..||.|:..|||||..|....|
Zfish   528 AKFTETEAL-EGAIYACDYCNNKRRRFCSKQVVLTEAQKQLMVHKLPHVLRLHLKRFRWSGRNHR 591

  Fly   405 -KISSFIQFPVEFDMTPFMSEKKNAYGD------FRFSLYAVVNHVGT-IDTGHYTAYVRH-QKD 460
             ||...:||..|.:|.|:..:..   |:      |.:.|.|||.|.|. ..:|||||:..: :..
Zfish   592 EKIGVHVQFEQELNMEPYCCKDS---GNLPHPQHFLYQLSAVVMHHGKGFGSGHYTAFCYNTEGG 653

  Fly   461 TWVKCDDHVITMASLKQVLDSEGYLLFY 488
            .||.|:|..:::.::::|..::.|:|||
Zfish   654 FWVHCNDSKLSVCAVEEVCKAQAYILFY 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	18/59 (31%)
		Peptidase_C19D	158..489	CDD:239125	113/405 (28%)
usp44	NP_956551.1	zf-UBP	26..88	CDD:280334	18/62 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..294		13/97 (13%)
		Hc1	<204..274	CDD:284776	9/71 (13%)
		UCH	294..681	CDD:278850	111/404 (27%)
		Peptidase_C19	296..682	CDD:271592	113/404 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810