Protein Alignment not and usp44

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_956551.1
• Gene: usp44 / 393227
• ZFINID: ZDB-GENE-040426-774
• Length: 695
• Species: Danio rerio
• Alignment Length: 678
• Identity: 155/678 - (22%)
• Similarity: 235/678 - (34%)
• Gaps: 255/678 - (37%)

  Fly   252 NCFECGSYGIQLYACLHCIYFGCR---GAHITSHLRSKKHNVALELSHGTLYCYACRDFIYD--- 310
            :|.:|.:.. .::|||.|.:..|.   ..|...|.:.:.|.:|||::...:|||.|.|::.:
Zfish    25 HCVDCNTTE-SVWACLSCSHVACGRYIEEHALQHFKEQHHPLALEVNELYVYCYLCDDYVLNDNA 88

  Fly   311 ----------------------ARS-----------------------------------REYAL 318
                                  .||                                   |..||
Zfish    89 TGDLKLLRSTLSAIKSQCYEVTTRSGRTLRSSSANGDQLSPSTQELQLRDEDRMFTALWHRRRAL 153

  Fly   319 I----------------------------NRKLEAKD--------LQKSIGWVPWVP-------- 339
            |                            .||.||::        |::.:...|  |
Zfish   154 IGRLFRLWFAQTERGKKRLEEERQQEEEEERKREARERRRQLKRQLKEELESAP--PRKSHRIRR 216

  Fly   340 -TTKETNLLLANA--------RRRLV--------------------------------------- 356
             :.|.|::..|.|        |||..
Zfish   217 QSLKATSVKPARAPAKSTKSVRRRSAPARVSTPTPRTPRERTPQQRPRPQAKAKRPQAPPSKTGD 281

  Fly   357 -----RPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDC---------------- 400
                 ||..|.|:.||.|||.||:||.|:|.|.|..:..:.|:  |.|.
Zfish   282 SPVKRRPTVTPGVTGLRNLGNTCYMNSILQVLSHLHVFRECFL--RLDLNQALELLASAVSRKLG 344

  Fly   401 --------------GS--------------------KSSHKCLVCEVSRLFQEFYSGSRSPLSLH 431
                          ||                    .|.|..|..|:..||...:||..:.:|..
Zfish   345 LSAQRVIQPKGLNQGSGLSGGASRSRNMELIQPKEPSSKHISLCHELHTLFPVMWSGKWALVSPF 409

  Fly   432 RLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSH 496
            .:||.:|.......||.||||.||....||         |.:||.:...:.:.:   :..::...
Zfish   410 AMLHSVWQLIPAFRGYAQQDAQEFLCELLD---------KVQHELERTRTLTPA---TVPANQRR 462

  Fly   497 CYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGE----TTTHGGVTPKTLIDCL 557
            ...|...:::.||.|.|.|.|.|.||:..|.|.:||||:||:..|    .:......|..|.:.|
Zfish   463 LIKQVLSVVNTIFHGQLLSQVRCLACDHRSNTIEPFWDLSLEFPERYHSNSKDAAQVPCGLTEML 527

  Fly   558 ERYTRAEHLGSAAKIKCSTCKSYQ-----------ESTKQFSLRTLPSVVSFHLKRFEHSALIDR 611
            .::|..|.| ..|...|..|.:.:           |:.||..:..||.|:..|||||..|....|
Zfish   528 AKFTETEAL-EGAIYACDYCNNKRRRFCSKQVVLTEAQKQLMVHKLPHVLRLHLKRFRWSGRNHR 591

  Fly   612 -KISSFIQFPVEFDMTPFMSEKKNAYGD------FRFSLYAVVNHVGT-IDTGHYTAYVRH-QKD 667
             ||...:||..|.:|.|:..:..   |:      |.:.|.|||.|.|. ..:|||||:..: :..
Zfish   592 EKIGVHVQFEQELNMEPYCCKDS---GNLPHPQHFLYQLSAVVMHHGKGFGSGHYTAFCYNTEGG 653

  Fly   668 TWVKCDDHVITMASLKQVLDSEGYLLFY 695
            .||.|:|..:::.::::|..::.|:|||
Zfish   654 FWVHCNDSKLSVCAVEEVCKAQAYILFY 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464	18/59 (31%)
		Peptidase_C19D	365..696	CDD:239125	113/405 (28%)
usp44	NP_956551.1	zf-UBP	26..88	CDD:460464	18/62 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..294		13/97 (13%)
		PRK07003	<216..>276	CDD:235906	7/59 (12%)
		UCH	295..681	CDD:425685	111/403 (28%)