DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and scny

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_729092.1	Gene:	scny / 38648	FlyBaseID:	FBgn0260936	Length:	1038	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	93/371 - (25%)
Similarity:	166/371 - (44%)	Gaps:	69/371 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 RRLVRPNQTIGL------------RGLLNLGATCFMNCIVQALVHTPLLSDYFMSDR-H--DCG- 194
            :|::.|.:.|.:            .|::|:|.||::|..:|||:|.|.|:::.:|:: |  ||.
  Fly   148 KRVLYPRENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNV 212

  Fly   195 SKSSHKCLVCEVSRLFQEFYSGSRS--PLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLH 257
            ::....|::|.:::......|...:  |..::..|..|   .||:....|:|||||....::.:.
  Fly   213 AEPGSGCIICAMTKTLLATQSNQSAVRPFLIYSKLKQI---CKHMVVGRQEDAHEFLRFLVEAME 274

  Fly   258 RHCVKAKAEHES-----KSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNG 317
            |..:.....::.     |..:.                       :.|||.|.|:|:|.|.:||.
  Fly   275 RAYLMRFRNYKELDQLVKETTP-----------------------LGQIFGGYLRSEVRCLSCNH 316

  Fly   318 VSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERY---TRAEHLGSAAKIKCSTCKSYQESTKQ 379
            ||.|:..|.|:.||:.:.        .:|.|..|.:   .|.|.:|    .||..||....:|||
  Fly   317 VSITFQHFQDLLLDIRKA--------DSLEDAFEGHFSRERLEDMG----YKCEGCKKKVSATKQ 369

  Fly   380 FSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAYGD-FRFSLYAVVNHV 443
            |||...|..:...||||   ::|..|::..|.|....|::.:.:..:.|... ..:.|.::|.|:
  Fly   370 FSLERAPITLCIQLKRF---SMIGNKLTKQISFKSRIDLSKYAARSQAAQAQPLTYRLVSMVTHL 431

  Fly   444 GTID-TGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 488
            |... .|||||.......::...||..:...::..|.::..|::|:
  Fly   432 GASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFF 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	90/347 (26%)
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	89/346 (26%)
		UCH	172..477	CDD:278850	89/345 (26%)
		Asp-B-Hydro_N	<617..>731	CDD:191249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840