Protein Alignment not and Usp47

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Alignment Length: 812
• Identity: 155/812 - (19%)
• Similarity: 255/812 - (31%)
• Gaps: 290/812 - (35%)

  Fly    12 EIETRKASEKSQKFTKKKPNYFQNWAARRRTA-----------------KVAKIRRKQRKCDKAF 59
            |.:.|...||    |||||....:..::.:|.                 |.:||:....|..|
  Fly   131 EKKKRVVGEK----TKKKPASGSSSPSKAKTTSEDSLAKTSISSESSPEKTSKIKTTAAKISK-- 189

  Fly    60 VPLQSSAKRAKTKENSVDSNTSVFSSSSSSSSGRSFGRGTERWAVGAEAGRGTAENETLAVAAAA 124
             |....|.|| :.|...:.:|.:.|.::||.|                           .||...
  Fly   190 -PGSEKAPRA-SPEECPELSTEINSKNTSSES---------------------------PVAKKT 225

  Fly   125 ATTTNAGRFITADLIKTVNSDKQRDRVAKGHRDAKNPLDATKHLRLSDCLR----------TVQK 179
            |..|:.........||..:..|:.|         ..|:|.....:||:.|:          .|..
  Fly   226 AKVTSKPTLELLSPIKPSSPIKELD---------CEPVDTLSKQQLSEQLQLYPQGRNLISPVDD 281

  Fly   180 LAIELESADAG--SDASAQANASADASSAVMSETGCRHYQSYVKEHSYDTFRVIDAYFAACVNRD 242
            ...:|..:||.  ||......|||   |..|...|            ||       |.|...:.|
  Fly   282 APSDLFISDAEQLSDDDLALGASA---SPTMLGPG------------YD-------YGAPTGDSD 324

  Fly   243 ARERKAIHCNCFECGSYGIQLYACLHCIYFGCRGAHITSHLRSKKHNVALELSHGTLYCYACRDF 307
            ..                            |..|....|.:             ||      .|.
  Fly   325 VE----------------------------GVTGVTDPSTI-------------GT------DDG 342

  Fly   308 IYDARSREYALINRKLEAKDLQKSIGW-------VPWVPT-TKETNLLLANARRRLVRPNQTIGL 364
            .|.|.|..|   .||....:|:   .|       ..:|.: |.||.   |.||:..:.|.   |.
  Fly   343 TYPALSNFY---RRKYGGDELR---AWQRVNTTGADFVSSATTETE---AEARQASLGPR---GY 395

  Fly   365 RGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHKCLVCEVSRLFQEFYSGSRSPLS 429
            .||:|...||::|.::|||..||...:...  |.:..:.:..|.:..::.:||....:..::.:.
  Fly   396 VGLVNQAMTCYLNSLLQALFMTPEFRNALY--RWEFDNDNEAKNIPYQLQKLFLNLQTSPKAAVE 458

  Fly   430 LHRLLHLI-WNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSS 493
            ...|.... |:..:   .::|.|..|......|.|         ||:.|:        |..:|
  Fly   459 TTDLTRSFGWDSTE---AWQQHDIQELCRVMFDAL---------EHKFKN--------TKQAN-- 501

  Fly   494 SSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDL---GETTTHGGVTPKTLID 555
                      :|..::.|.:...|.|..||...|..|.|.||.|.:   |.::.:|.:.     :
  Fly   502 ----------LISNLYEGKMNDYVKCLECNTEKTREDTFLDIPLPVRPFGSSSAYGSIE-----E 551

  Fly   556 CLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKR--FEHSALIDRKISSFIQ 618
            .|..:.:.|.|....:..|..||...::.|....::.|.:::.||||  |::..:...|::..:.
  Fly   552 ALRAFVQPETLDGNNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVT 616

  Fly   619 FPVEFDMTPFMSEK--------------------------------------------------- 632
            ||...::..|::..
  Fly   617 FPQTLNLNTFINRSGNSGEQNSQLNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLNDE 681

  Fly   633 --------------KNAYGDFRFSLYAVVNHVGTIDTGHYTAYVR-HQKDTWVKCDDHVITMASL 682
                          |...|.:.:.|:|::.|.|:...|||.||:: ...:.|...:|..:|..:.
  Fly   682 DEGIDMSSSTSKSAKQGSGPYLYELFAIMIHSGSASGGHYYAYIKDFDNNEWFCFNDQNVTSITQ 746

  Fly   683 KQVLDSEG-----------------YLLFYHK 697
            :.:..|.|                 |:|.|.:
  Fly   747 EDIQRSFGGPNGSYYSSAYTSSTNAYMLMYRQ 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464	6/56 (11%)
		Peptidase_C19D	365..696	CDD:239125	76/419 (18%)
Usp47	NP_523937.2	DUF4045	<122..249	CDD:433066	32/152 (21%)
		peptidase_C19C	394..780	CDD:239124	78/424 (18%)
		USP47_C	1300..1534	CDD:466158