DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and Usp20-33

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_610943.2	Gene:	Usp20-33 / 36580	FlyBaseID:	FBgn0033916	Length:	975	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	118/466 - (25%)
Similarity:	177/466 - (37%)	Gaps:	132/466 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 GLRGLLNLGATCFMNCIVQALVHTPLLSDYFM--SDRHD-CGSKSSHKC----LVCEVSRLFQEF 213
            ||.||.|:..||:||..:|||.:.|.::.||:  ||..: ...:|:.:|    |.....||.||.
  Fly    78 GLVGLQNIANTCYMNSALQALSNLPPMTHYFINCSDLVEYIAEQSARRCKPGGLAKSYRRLMQEI 142

  Fly   214 YSGSRSP---LSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVK------------- 262
            :.....|   ::...:|:.|........||:|.|..||....:|.||....:
  Fly   143 WQDVDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEFLRCFMDQLHEELTEQVSMLPQTQNQPQ 207

  Fly   263 ----------------------AKAEHESKS---------------------------NSSGSGS 278
                                  |...|.|:|                           .::||.|
  Fly   208 YQSLQQQQPSETDDENDDEAAPASLSHASESEYDTCESSMSERSAEVLLKTEYFVTPCRTNGSNS 272

  Fly   279 G-----------------TNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFW 326
            |                 ..:::|:..........||..:|.|.|.|.|.|..|:.|||..:.|.
  Fly   273 GLPEGHSVQLQQAPLQHQQKNASSAEQKPIEAARSIISDVFDGKLLSSVQCLTCDRVSTREETFQ 337

  Fly   327 DISLDL----------------------GET---TTHGGVT------------PK-TLIDCLERY 353
            |:||.:                      .||   |..|.::            |. ||.||:..:
  Fly   338 DLSLPIPNRDFLNVLHQTHSLSVQSLNAAETSARTNEGWLSWMWNMLRSWIYGPSVTLYDCMASF 402

  Fly   354 TRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVE-FD 417
            ..|:.|.......|..|...:...|...:.|||.|:..|||||.:......||||.:.||:| ||
  Fly   403 FSADELKGDNMYSCERCNKLRTGIKYSRVLTLPEVLCIHLKRFRNDLSYSSKISSDVYFPLEGFD 467

  Fly   418 MTPFMSEKKNAYGDFR-FSLYAVVNHVGTIDTGHYTAYVRHQ-KDTWVKCDDHVITMASLKQVLD 480
            |.|::  .|:...:.. ::|.:|:.|.||:..||||.:.|:. ...|.:.||..:|..|.:.|..
  Fly   468 MRPYI--HKDCKSEVAIYNLSSVICHHGTVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQS 530

  Fly   481 SEGYLLFYHKN 491
            .:.|:|||||:
  Fly   531 CQAYVLFYHKH 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	113/460 (25%)
Usp20-33	NP_610943.2	UCH	79..538	CDD:278850	113/460 (25%)
		Peptidase_C19	80..>204	CDD:271592	34/123 (28%)
		Peptidase_C19R	307..538	CDD:239139	69/232 (30%)
		DUSP	560..643	CDD:197831
		DUSP	667..755	CDD:197831
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21646
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010