DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and DUBAI

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_610784.1	Gene:	DUBAI / 36361	FlyBaseID:	FBgn0033738	Length:	852	Species:	Drosophila melanogaster

Alignment Length:	440	Identity:	107/440 - (24%)
Similarity:	165/440 - (37%)	Gaps:	123/440 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 LANARRRLVRP----NQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRH----DCGSKS 197
            ||.|.....:|    |..:   ||:|||.||:||.::|||..|   ||:   .|.    :|.|
  Fly   340 LAKAMHENAQPWGRRNARV---GLVNLGNTCYMNSVLQALAMT---SDF---SRQILLIECNS-- 393

  Fly   198 SHKCLVCEVSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYE---QQDAHEFFIATLDVLHRH 259
               .|:.:|.:.....:...|..|:..|:|     :|.....:.   |||:.||....||:||.|
  Fly   394 ---VLLMKVQQQIALMHHSLRYELTPSRVL-----NATRPPSFTPGLQQDSSEFLGYLLDLLHEH 450

  Fly   260 CVKAKA--------------------------------EHESKSNSSGSGSGTNSSNSSSSHCYG 292
            .:.:.:                                .:.||.:...|||  ||.|
  Fly   451 EINSSSVTGHSVGPPKTGREVDDVPALLSEDILSSGVIPYNSKDHELSSGS--NSDN-------- 505

  Fly   293 QCN-------------------------------CIIDQIFTGMLQSDVVCQACNGVSTTYDPFW 326
             ||                               ..||:.|.|.|.:...|..|...|...|.|.
  Fly   506 -CNHKPTPTPPATPTKATNGLKQQGQQVDQAKPPSTIDKTFAGKLSTTYRCLNCGWESRNEDSFR 569

  Fly   327 DISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSF 391
            ::.|...:.....|.|..::.|.:|.|...|.|....:..|..||...::.:...:...|..:..
  Fly   570 ELQLSFPDDKEDCGATNYSVQDLIEYYCSPEKLDGDNQYFCPQCKKLCDAERHIGVTQAPKNLIL 634

  Fly   392 HLKRFEHSALIDRK--ISSFIQFPVEFD--MTPFMSEKKN--AYGDFRFSLYAVVNHVG-TIDTG 449
            .||:|::    |:|  ..:.:...|..|  :|..||.|.:  ......:.|||.|.|.| ::|:|
  Fly   635 TLKQFKY----DQKYHFRTKLMHKVFHDESVTVKMSAKDSLQEMSTVHYDLYAGVVHAGYSMDSG 695

  Fly   450 HYTAYVRHQKDTWVKCDDHVITMASLKQV--LDSEG--YLLFY----HKN 491
            ||..:...|...|.|.:|:|:|.:..:::  |.|..  |:|||    |.|
  Fly   696 HYFTFAADQAKNWYKFNDNVVTHSKPEEMHNLTSPNTPYILFYKMCGHSN 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	100/415 (24%)
DUBAI	NP_610784.1	UCH	358..738	CDD:278850	98/413 (24%)
DUBAI	NP_610784.1	Peptidase_C19H	359..739	CDD:239129	99/410 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840