DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and Usp48

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_006239296.1	Gene:	Usp48 / 362636	RGDID:	735213	Length:	1064	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	99/373 - (26%)
Similarity:	150/373 - (40%)	Gaps:	90/373 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 WVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIV----------QALVHTP- 180
            |:..:......|:...|..||  :.|..:   ||.||||||::|..:          |||...|
  Rat    91 WLGEIDENSFHNIDDPNCERR--KKNSFV---GLTNLGATCYVNTFLQVWFLNLELRQALYLCPS 150

  Fly   181 LLSDYFMSD--RHDCGSKSSHKCLVCE-VSRLFQEFYSGSR---SPLSLHRLLHLIWNHAKHLAG 239
            ..|||...|  |   |.|......:|| :..||....:.:|   .|....:.|.|...
  Rat   151 TCSDYTKGDGIR---GGKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTG------- 205

  Fly   240 YEQQDAHEF---FIATL-DVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQ 300
             :||||.||   |::.| |.|      :|.::....|                        ::.|
  Rat   206 -QQQDAQEFSKLFMSLLEDTL------SKQKNPDVRN------------------------VVQQ 239

  Fly   301 IFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKI 365
            .|.|......||..|...|.....|:::.|::   ..|     |.|.||:..:.:.|.|....:.
  Rat   240 QFCGEYAYVTVCSQCGRESKLVSKFYELELNI---QGH-----KQLTDCISEFLKEERLEGDNRY 296

  Fly   366 KCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDR------KISSFIQFPVEFDMTPFMSE 424
            .|..|:|.|.:|::..|.:||..::..|.||    :.||      |::::|.|....||.|::..
  Rat   297 FCENCQSKQNATRKIRLLSLPCTLNLQLMRF----VFDRQTGHKKKLNAYIGFSESLDMEPYVEH 357

  Fly   425 KKNAYGDFRFSLYAVVNHVG-TIDTGHYTAYVRH-QKDTWVKCDDHVI 470
            |.   |.|.:.|.||:.|.| :..:|||.|:|:. |...|.|.:|..|
  Rat   358 KG---GSFVYELSAVLIHRGVSAYSGHYIAHVKDPQSGDWYKFNDEDI 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	93/342 (27%)
Usp48	XP_006239296.1	UCH	117..446	CDD:278850	93/345 (27%)
		Peptidase_C19L	118..447	CDD:239133	93/341 (27%)
		DUSP	512..582	CDD:283896
		USP48_C	958..1064	CDD:176390
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910