DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and Usp2

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001285528.1	Gene:	Usp2 / 33132	FlyBaseID:	FBgn0031187	Length:	950	Species:	Drosophila melanogaster

Alignment Length:	360	Identity:	109/360 - (30%)
Similarity:	173/360 - (48%)	Gaps:	46/360 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 RPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKS---SHKCLVCEVSRLFQ 211
            |..::.||.||.|:|.|||||.::|.|.||..|: .|:...|  ||:|   ..:.::.|.::|.|
  Fly   617 RDEKSEGLCGLRNIGNTCFMNSVIQCLSHTQELT-RFLRSHH--GSRSLSTKDQQILHEFAKLIQ 678

  Fly   212 EFYSG---SRSPLSLHRLLHLIWNHAKH--LAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKS 271
            |.::.   :.:|:.|.|..     ..||  .:.|.||||.||....||.||           |..
  Fly   679 EMWTANVHTVTPMELKRAF-----STKHRMYSDYNQQDAQEFLRFFLDSLH-----------SAL 727

  Fly   272 NSSGSGSGTNSSNSSSSHCYGQC---------NCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWD 327
            ||...|...|..::.|.:.....         |.::..:|.|.|:|.:.|..|...|.|:|||||
  Fly   728 NSGVKGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWD 792

  Fly   328 ISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFH 392
            :|:.|..::.      ..|..||:.:.|.|.|.......|:.||:.::.||.|:::..|..:..|
  Fly   793 LSVPLPSSSR------CKLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIH 851

  Fly   393 LKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRH 457
            ||||..:..  .|:|:.::||.........|...|:..:..:||||:.||:|:...|||.|..:|
  Fly   852 LKRFSETRW--SKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKH 914

  Fly   458 Q-KDTWVKCDDHVITMA-SLKQVLDSEGYLLFYHK 490
            . ...|.:.:|::::.| |...::.|..|:|||.:
  Fly   915 PVSRKWHEFNDNIVSDALSENHLVSSSAYILFYER 949

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	105/349 (30%)
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	105/349 (30%)
Usp2	NP_001285528.1	Peptidase_C19R	626..948	CDD:239139	105/348 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21646
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.970