Protein Alignment not and Usp44

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_038934982.1
• Gene: Usp44 / 314746
• RGDID: 1308216
• Length: 731
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 159/676 - (23%)
• Similarity: 231/676 - (34%)
• Gaps: 247/676 - (36%)

  Fly   251 CNCFECGSYGIQLYACLHCIYFGCR---GAHITSHLRSKKHNVALELSHGTLYCYACRDFIY--- 309
            ||..|      .::|||.|.:..|.   ..|...|.....|.||.|::...::||.|.|::.
  Rat    46 CNTTE------SIWACLSCSHVACGQYIQEHALKHFEESSHPVAFEVNDMYVFCYLCNDYVLNDN 104

  Fly   310 ---DARSREYAL--------------------INRKLEAKDLQKSIGWVP--------------- 336
               |.:|....|                    :|.:.::..|..|...:|
  Rat   105 TAGDLKSLRSTLSAIKGKSYPCVVQSDSVLQPVNAQADSYSLHDSTQSLPGSEDPMCTALWHRRR 169

  Fly   337 ---------WV----------PTTKETNLLLANARRR---------------------------- 354
                     |.          ..|:|..:.....:||
  Rat   170 ALMGKTFRTWFEQSPIGRKRQEQTQEKTVAKREVKRRQQELEQQMKAELECTPPRKSLRLQGLSE 234

  Fly   355 -----------------------------------------LV--RPNQTIGLRGLLNLGATCFM 376
                                                     |:  ||..|.|:.||.|||.||:|
  Rat   235 AATVEILPVQAPPPPPASPAKEKALALPPSEDGKLKRVSDSLIKRRPAVTPGVTGLRNLGNTCYM 299

  Fly   377 NCIVQALVHTPLL-----------------SDYFMSDRH----DCGSKSSH---------KCLVC 411
            |.::|.|.|..:.                 ||...|.:|    |..:.::|         |...|
  Rat   300 NSVLQVLSHLLIFRQCFLKLDLNQWLAVAASDKARSYKHSAVTDAATAAAHQLNEGQEKEKGFAC 364

  Fly   412 -------------------------------------EVSRLFQEFYSGSRSPLSLHRLLHLIWN 439
                                                 |:..|||..:||..:.:|...:||.:|.
  Rat   365 SRHPGLSSGLSGGASKGRNMELIQPREPSSPYSSLCHELHTLFQVMWSGEWALVSPFAMLHSVWK 429

  Fly   440 HAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSS---NSSSSHCYGQC 501
            ......||.||||.||....||.:.|       |.|:        :||...   .:|......|.
  Rat   430 LIPAFRGYAQQDAQEFLCELLDKIQR-------ELET--------TGTKLPALIPTSQRRLIEQV 479

  Fly   502 NCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGG----VTPKTLIDCLERYTR 562
            ..:::.||.|.|.|.|.|.|||..|.|.:||||:||:..|.....|    ..|..:.|.|.::|.
  Rat   480 LNVVNNIFHGQLLSQVTCLACNNKSNTIEPFWDLSLEFPERYQCSGKDAASQPCLVTDMLGKFTE 544

  Fly   563 AEHLGSAAKIKCSTCKSYQ-----------ESTKQFSLRTLPSVVSFHLKRFEHSALIDR-KISS 615
            .|.|.....: |..|.|.:           |:.||..:..||.|:..|||||..|...:| ||..
  Rat   545 TEALEGKIYV-CDHCNSKRRKFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGV 608

  Fly   616 FIQFPVEFDMTPF-MSEKKNAYGD--FRFSLYAVVNHVGT-IDTGHYTAYVRHQK-DTWVKCDDH 675
            .:.|....:|.|: .||..||...  |.::|.|||.|.|. ..:||||||..:.: ..||.|:|.
  Rat   609 HVVFEETLNMEPYCCSETLNALRPECFIYNLSAVVIHHGKGFGSGHYTAYCYNSEGGFWVHCNDS 673

  Fly   676 VITMASLKQVLDSEGYLLFYHKNVLE 701
            .::|.::::||.::.|:|||.:.|.|
  Rat   674 KLSMCTMEEVLRAQAYILFYTQRVTE 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464	16/65 (25%)
		Peptidase_C19D	365..696	CDD:239125	121/421 (29%)
Usp44	XP_038934982.1	zf-UBP	43..104	CDD:460464	18/63 (29%)
		UCH	288..693	CDD:425685	120/420 (29%)