DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and Usp36

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_038942129.1	Gene:	Usp36 / 303700	RGDID:	1309937	Length:	1098	Species:	Rattus norvegicus

Alignment Length:	417	Identity:	119/417 - (28%)
Similarity:	203/417 - (48%)	Gaps:	65/417 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 ACRDFIYDARS--REYALINRKLEAKDLQKSIGWVPWV--PTTKETNLLLAN---ARRRLVRPNQ 153
            |.:.|.|...|  .:|.|:|.|.|.....:| |..|..  |.|:..:....:   |.::::.|.:
  Rat    45 ASKSFSYQLESLKSKYVLLNPKAEGAGRHRS-GDEPQARKPGTERMSGSGGDGVPAPQKVLFPVE 108

  Fly   154 TIGLR---------GLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHK---CLVCEV 206
            .:.||         ||.|||.|||:|..:|.|.:||.|::|.:|..|   ::|.|:   |::|.:
  Rat   109 RLSLRWERVFRVGAGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKEH---ARSCHQGSFCMLCVM 170

  Fly   207 -SRLFQEFYSGSRS--PLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHE 268
             :.:.|.|.:...:  |:|..|.|..|   |:|.....|:|||||...|:|.:.:.|:...|:.:
  Rat   171 QNHMVQAFANSGNAIKPVSFIRDLKKI---ARHFRFGNQEDAHEFLRYTIDAMQKACLNGYAKLD 232

  Fly   269 SKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLG 333
            .::                     |...::.|||.|.|:|.|.|..|..||.||||:.||:|::.
  Rat   233 RQT---------------------QATTLVHQIFGGYLRSRVKCSVCRSVSDTYDPYLDIALEIR 276

  Fly   334 ETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEH 398
            :..        .::..||.:.:::.|.......|:.||....::|:||:....:|::..||||.:
  Rat   277 QAA--------NIVRALELFVKSDVLSGENAYMCAKCKKKVPASKRFSIHRTSNVLTLSLKRFAN 333

  Fly   399 SALIDRKISSFIQFPVEFDMTPFMSEKKNAYGD-FRFSLYAVVNHVG-TIDTGHYTAYVRHQKDT 461
            .:  ..||:..:.:|...::.|:||:..   || ..:.||||:.|.| :...|||..||:.....
  Rat   334 FS--GGKITKDVGYPEFLNIRPYMSQSS---GDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQ 393

  Fly   462 WVKCDDHVITMASLKQVLDSEGYLLFY 488
            |.:.:|.::..:::|.||..:.|:|||
  Rat   394 WYQMNDSLVHSSNVKVVLSQQAYVLFY 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	2/6 (33%)
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	102/348 (29%)
Usp36	XP_038942129.1	Peptidase_C19E	121..421	CDD:239126	101/340 (30%)
Usp36	XP_038942129.1	Herpes_BLLF1	<493..>807	CDD:282904
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D929408at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920