DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and ubp16

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_587805.1	Gene:	ubp16 / 2538947	PomBaseID:	SPCC1682.12c	Length:	457	Species:	Schizosaccharomyces pombe

Alignment Length:	363	Identity:	94/363 - (25%)
Similarity:	169/363 - (46%)	Gaps:	58/363 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 RLVRPNQTIGLR---------GLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHKCL 202
            |::.|.:.:.:.         ||:|||.|||||.::|.:..||.|..|.:|.:|....: .:.|:
pombe   105 RILFPEEKLSMEWDNIMPNAPGLVNLGNTCFMNSVLQLMTQTPPLVQYLLSGQHSLSCR-MNACV 168

  Fly   203 VCEVSRLFQEFY--SGSR-----SPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHC 260
            :|.:.:.....|  .|::     .|..:..:|.:|   :.|...|.|:|||||....:|...:.|
pombe   169 LCRMEQHVARAYPNKGTKRASAFKPSGIQSMLKVI---SSHFRPYRQEDAHEFMRYLVDAWQKSC 230

  Fly   261 VK--AKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYD 323
            ::  ...:|.|:..|                       ::.:||.|.|:..::|..|...|.||.
pombe   231 LQNHKNLDHPSRETS-----------------------VVHRIFGGYLRQQILCSVCKKPSNTYQ 272

  Fly   324 PFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSV 388
            ...|:|:|         ....:|.|.|:.:..||.|....|.:|..||...:::||.::...|::
pombe   273 ALLDLSVD---------AKGSSLADSLKHFVHAEKLTKQNKYRCENCKQLVDASKQMTIYRAPNI 328

  Fly   389 VSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAYGDFRFSLYAVVNHV-GTIDTGHYT 452
            ::.|.|||..:.....|||..|.:|..|::.|:||:...:..   :.|..|:.|. |:..:|||.
pombe   329 LTIHFKRFTFNGFQSSKISKQISYPESFNLGPYMSDPNCSCW---YELIGVLVHAGGSTRSGHYY 390

  Fly   453 AYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFYHK 490
            ::.:.....|:|.||..::.:|:.:||:.:.|:|.|.:
pombe   391 SFCKSSNGVWLKFDDDFVSNSSIDRVLNQQAYILQYKR 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	91/349 (26%)
ubp16	NP_587805.1	Peptidase_C19E	124..426	CDD:239126	91/340 (27%)
ubp16	NP_587805.1	UCH	126..426	CDD:278850	91/338 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59954
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920