DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and Usp9x

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_006527649.1	Gene:	Usp9x / 22284	MGIID:	894681	Length:	2575	Species:	Mus musculus

Alignment Length:	451	Identity:	102/451 - (22%)
Similarity:	162/451 - (35%)	Gaps:	152/451 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 VRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFM------SDRHDCGS---KSSHKCLVC 204
            |.|....|..||.|.||||:||.::|.|...|.:.:..:      ||..|..|   |..::..|.
Mouse  1553 VGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVD 1617

  Fly   205 EVSRLF---QEFYSGSRSPLS-----------LHRLLHLIWNH--AKHLAGY------------- 240
            ....:|   |:|  ..:.|||           :.|.|.:|:.|  |..|..|
Mouse  1618 PRDDVFGYPQQF--EDKPPLSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWG 1680

  Fly   241 ------EQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIID 299
                  ||.||.|||.:.:|.|. ..:||.. |.:                           ::.
Mouse  1681 EPVNLREQHDALEFFNSLVDSLD-EALKALG-HPA---------------------------MLS 1716

  Fly   300 QIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAK 364
            ::..|......:||.|.......:.|..:::|:   ..|     :.|:|.||:|.:.:.|..|..
Mouse  1717 KVLGGSFADQKICQGCPHRYECEESFTTLNVDI---RNH-----QNLLDSLEQYVKGDLLEGANA 1773

  Fly   365 IKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHS-----ALIDRKISSFIQFPVEFDMTPF--- 421
            ..|..|....::.|:..::.||.|::..||||::.     |:   |.:.:.:||.|.||.|:
Mouse  1774 YHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAI---KFNDYFEFPRELDMEPYTVA 1835

  Fly   422 ---------------------MSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRH------QK 459
                                 .||.:.| |..::.|..|:.|.|....|||.:|:..      :|
Mouse  1836 GVAKLEGDNVNPESQLIQQNEQSESEKA-GSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGEK 1899

  Fly   460 DTWVKCDDHVITMASLK----------------QVLDS--------------EGYLLFYHK 490
            :.|.|.||..:|...:.                :|.|.              ..|:|||.:
Mouse  1900 NRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYER 1960

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	98/439 (22%)
Usp9x	XP_006527649.1	Ubiquitin_like_fold	<905..969	CDD:391949
Usp9x	XP_006527649.1	peptidase_C19C	1560..1963	CDD:239124	100/444 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910