Protein Alignment not and cyk-3

DIOPT Version :9

• Sequence 1: NP_001287106.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_001022992.1
• Gene: cyk-3 / 175853
• WormBaseID: WBGene00000874
• Length: 1178
• Species: Caenorhabditis elegans
• Alignment Length: 681
• Identity: 117/681 - (17%)
• Similarity: 192/681 - (28%)
• Gaps: 321/681 - (47%)

  Fly   101 IYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGA 165
            :.:.|.|...:...:|.|....|.|    ...:|..:|..|:::..   ||    |..||:|.|.
 Worm   524 LLEVRERGTGVWPEELRASLSGKQI----TAASTLSSNAQLSDSSG---RP----GAVGLVNYGN 577

  Fly   166 TCFMNCIVQALVHTPLLSDYFMSD------------RHDCGSKSSHKCLVCEVSRLFQEFYSGSR 218
            .|:.|..:|.|.....|:.||:.:            |.|....:      .|.::|.:|.::..:
 Worm   578 FCYRNAGIQCLARVSPLTQYFLDEDNLDAIKRGNLRRGDAAETT------IEYAKLLREMWAAKK 636

  Fly   219 SPLSLHRLLHLIWNHAKHLAG-----YEQQDAHEFFIATLDVLHRHCVKA-KAEHESKSNSSGSG 277
            ..::.:.     :|.|..|:.     .||.|..||....||.||....:: |:.|.|...|.|:.
 Worm   637 KNIAPND-----FNDAIRLSSDMFECSEQHDCQEFVAFLLDQLHTSMYESNKSLHPSPEESEGTD 696

  Fly   278 SGTNSSNSSSSHC----------------YGQCN-CIIDQIFTGMLQSDVVCQACNGVSTTYDPF 325
            |...|.:|.....                |.:.| .::.|:|||.|:|.::|:.|...|:.::||
 Worm   697 SNKLSDSSKKKEADKEEADEEKAERSWTEYEKQNESLVTQLFTGQLRSRLICRTCQSSSSVFEPF 761

  Fly   326 WDISLDLG--------------------------------------------------------- 333
            ..:||.:|
 Worm   762 TSLSLPIGFEDVDLYQVIVVHRDGRIPRRYGFRLSRDSKVGNLREVVAVSSGISMSHLTIQCMSS 826

  Fly   334 -------------------------------------ETT------------------------T 337
                                                 |:|                        |
 Worm   827 KGTLMSRSPNHRSSNLRDELPLSSFPSGARLYALELPESTGEDQWRVAMHRKLQYNHEPYILGST 891

  Fly   338 HGGV------------------------------------------------------------- 341
            .|.:
 Worm   892 AGFIVSRFGLPLIVGLDEEVTGKKLYEDVMYQMHRFMEHSVNSSSSRAHDPCEDENSGYPFTLCL 956

  Fly   342 ----------------------------------------------------------------- 341
                                                                             
 Worm   957 VDPNYEWCGQCPALRFCRGCPIRPDESKVFIPANCPIAVDWLPIALYLRYNHSQEQACEDDPSVA 1021

  Fly   342 -------TPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHS 399
                   .|.:|..|:|:::..|.|.:|  |:|..|:......|..::..||..:..||||||..
 Worm  1022 ETWSRHFAPSSLEHCIEKFSCPETLDAA--IQCDRCEKKTMRDKVMTIWKLPKYLIIHLKRFEFL 1084

  Fly   400 ALIDR--KISSFIQFPVE-FDMTPFMSEKK-NAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKD 460
            ....|  |....:.||:: ||..||:.:.. |.|     ...|:.||.|.:..||:.||.:..:|
 Worm  1085 REQGRMGKCKRTVNFPLKHFDPAPFVDKPDGNTY-----ECIALANHYGQLSCGHFIAYAKSNED 1144

  Fly   461 TWVKCDDHVITMASLKQVLDSEG-YLLFYHK 490
            .|:..:|..:...|.::| |.:| |||||.:
 Worm  1145 KWLLLNDCSVREVSEEEV-DKQGAYLLFYER 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	0/1 (0%)
		Peptidase_C19D	158..489	CDD:239125	104/621 (17%)
cyk-3	NP_001022992.1	EFh_PEF	23..201	CDD:330173
		EF-hand_7	177..241	CDD:316058
		Peptidase_C19	322..1175	CDD:321984	117/681 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940