Protein Alignment not and cyk-3

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_001022992.1
• Gene: cyk-3 / 175853
• WormBaseID: WBGene00000874
• Length: 1178
• Species: Caenorhabditis elegans
• Alignment Length: 681
• Identity: 117/681 - (17%)
• Similarity: 192/681 - (28%)
• Gaps: 321/681 - (47%)

  Fly   308 IYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGA 372
            :.:.|.|...:...:|.|....|.|    ...:|..:|..|:::..   ||    |..||:|.|.
 Worm   524 LLEVRERGTGVWPEELRASLSGKQI----TAASTLSSNAQLSDSSG---RP----GAVGLVNYGN 577

  Fly   373 TCFMNCIVQALVHTPLLSDYFMSD------------RHDCGSKSSHKCLVCEVSRLFQEFYSGSR 425
            .|:.|..:|.|.....|:.||:.:            |.|....:      .|.::|.:|.::..:
 Worm   578 FCYRNAGIQCLARVSPLTQYFLDEDNLDAIKRGNLRRGDAAETT------IEYAKLLREMWAAKK 636

  Fly   426 SPLSLHRLLHLIWNHAKHLAG-----YEQQDAHEFFIATLDVLHRHCVKA-KAEHESKSNSSGSG 484
            ..::.:.     :|.|..|:.     .||.|..||....||.||....:: |:.|.|...|.|:.
 Worm   637 KNIAPND-----FNDAIRLSSDMFECSEQHDCQEFVAFLLDQLHTSMYESNKSLHPSPEESEGTD 696

  Fly   485 SGTNSSNSSSSHC----------------YGQCN-CIIDQIFTGMLQSDVVCQACNGVSTTYDPF 532
            |...|.:|.....                |.:.| .::.|:|||.|:|.::|:.|...|:.::||
 Worm   697 SNKLSDSSKKKEADKEEADEEKAERSWTEYEKQNESLVTQLFTGQLRSRLICRTCQSSSSVFEPF 761

  Fly   533 WDISLDLG--------------------------------------------------------- 540
            ..:||.:|
 Worm   762 TSLSLPIGFEDVDLYQVIVVHRDGRIPRRYGFRLSRDSKVGNLREVVAVSSGISMSHLTIQCMSS 826

  Fly   541 -------------------------------------ETT------------------------T 544
                                                 |:|                        |
 Worm   827 KGTLMSRSPNHRSSNLRDELPLSSFPSGARLYALELPESTGEDQWRVAMHRKLQYNHEPYILGST 891

  Fly   545 HGGV------------------------------------------------------------- 548
            .|.:
 Worm   892 AGFIVSRFGLPLIVGLDEEVTGKKLYEDVMYQMHRFMEHSVNSSSSRAHDPCEDENSGYPFTLCL 956

  Fly   549 ----------------------------------------------------------------- 548
                                                                             
 Worm   957 VDPNYEWCGQCPALRFCRGCPIRPDESKVFIPANCPIAVDWLPIALYLRYNHSQEQACEDDPSVA 1021

  Fly   549 -------TPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHS 606
                   .|.:|..|:|:::..|.|.:|  |:|..|:......|..::..||..:..||||||..
 Worm  1022 ETWSRHFAPSSLEHCIEKFSCPETLDAA--IQCDRCEKKTMRDKVMTIWKLPKYLIIHLKRFEFL 1084

  Fly   607 ALIDR--KISSFIQFPVE-FDMTPFMSEKK-NAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKD 667
            ....|  |....:.||:: ||..||:.:.. |.|     ...|:.||.|.:..||:.||.:..:|
 Worm  1085 REQGRMGKCKRTVNFPLKHFDPAPFVDKPDGNTY-----ECIALANHYGQLSCGHFIAYAKSNED 1144

  Fly   668 TWVKCDDHVITMASLKQVLDSEG-YLLFYHK 697
            .|:..:|..:...|.::| |.:| |||||.:
 Worm  1145 KWLLLNDCSVREVSEEEV-DKQGAYLLFYER 1174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464	0/1 (0%)
		Peptidase_C19D	365..696	CDD:239125	104/621 (17%)
cyk-3	NP_001022992.1	FRQ1	<124..201	CDD:444056
		EFh	179..241	CDD:415501
		UBP12	322..1175	CDD:227847	117/681 (17%)