DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and Y67D2.2

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_497422.3	Gene:	Y67D2.2 / 175310	WormBaseID:	WBGene00022052	Length:	474	Species:	Caenorhabditis elegans

Alignment Length:	435	Identity:	91/435 - (20%)
Similarity:	140/435 - (32%)	Gaps:	119/435 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 GLLNLGATCFMNCIVQALVHTPLLSDYFMSDR-HDCGSKSSHKCLVCEVSRLFQEFYSGSRSPLS 222
            ||.|.|.||:||.::|.|...|....:..|.: .|.|.:..   .|..:|.|.......:.|.|:
Worm    46 GLANQGNTCYMNALLQGLASCPSFVGWLKSLKPQDIGIQGG---FVDHLSNLLHLLNEPTGSTLT 107

  Fly   223 LHRLLHLIWNHAKHLAGYEQQDAHEF---FIAT----LDVLHRHCVKAKAE--HESKSN------ 272
            ...::..:..|...:....:.|.:|.   |:.|    |....|..:....|  |.|.|.
Worm   108 AQSIVESLKAHGWSITVGVEHDLYELFNVFVTTWEDELKSSRRILMNQSIENCHSSSSEDDEDVV 172

  Fly   273 -SSGSGSGTNS-----------------SNSSSSHCYG------QC---NC-------------- 296
             .|.|..|:.|                 ..|..|.|.|      :|   ||
Worm   173 VESTSLRGSPSIIRKLMSFQRCASMARIDASLRSPCVGLTATEYRCCNTNCGYRTVKYESFTVLT 237

  Fly   297 ----------------IIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGV-TPK 344
                            ::.:.|...:..|.:|..|.........|         ...||.| .|:
Worm   238 LAIPNSQMGTSTNTESLLRRFFCSEIIRDAICDKCRASDRKQQGF---------LKKHGIVKLPQ 293

  Fly   345 TLIDCLER----------YTRAEHLGSAAKIKCSTC---------KSYQESTKQFSL--RTLPSV 388
            ||:..:||          .:...|.|....:: ..|         |||:||:..:.|  .|...|
Worm   294 TLMIRIERVGMLPNGSMKLSEHVHFGECLSLQ-DVCFRKNPKINQKSYEESSLHWQLPDGTSRVV 357

  Fly   389 VSFHLKRFEHSALIDRKISSFIQFPVEF---DMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGH 450
            ......|...|.:...:.:.|......:   |...|::|::.|. .:.:.|.||..|.|...:||
Worm   358 GGAEETRSRRSPIHPSQAAIFGDLASNYALIDGGSFVAERREAQ-KYAYQLRAVSEHRGGPYSGH 421

  Fly   451 YTAYVR-----HQKDTWVKCDDHVITMASLKQVLDSEGYLLFYHK 490
            :..|.|     |.  ||....|..:|......|...:.|:|||.:
Worm   422 FVTYRRASAPNHH--TWYYTSDAQVTRVPYSHVAACQSYMLFYER 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	90/432 (21%)
Y67D2.2	NP_497422.3	Peptidase_C19F	46..463	CDD:239127	90/432 (21%)
Y67D2.2	NP_497422.3	UCH	46..462	CDD:278850	89/431 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810