Protein Alignment not and F07A11.4

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_001364591.1
• Gene: F07A11.4 / 174780
• WormBaseID: WBGene00008547
• Length: 1135
• Species: Caenorhabditis elegans
• Alignment Length: 695
• Identity: 110/695 - (15%)
• Similarity: 175/695 - (25%)
• Gaps: 370/695 - (53%)

  Fly   363 GLRGLLNLGATCFMNCIVQALVHTPLLSDYFM--------SDRHDCGSKSSHKCLVCEVSRLFQE 419
            |..||.|:|.|||||.::|.||:...|.:||:        ::.:..||:.       .:::.|.:
 Worm   421 GYTGLRNIGNTCFMNAVLQMLVNNIELREYFLRNHYQPEINETNPLGSEG-------RLAKAFAD 478

  Fly   420 F----YSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNS 480
            |    :||.:..:...::.:::...|...|.:.|.|||||....||.||....:.|.:..:.:..
 Worm   479 FMHQMWSGHQKAIEPTQIKNIVAEKASQFANFAQHDAHEFLSFLLDGLHEDVNRVKKKPLTGTVE 543

  Fly   481 SGSGSGTNSSNSS-SSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDP------------- 531
            |......:.||.: .:|.....:..:| :|.|.|:|.|.|..|:.||.|:||
 Worm   544 SHGRHDLDVSNEAWKNHILRNDSIFVD-LFHGQLKSHVQCPNCDRVSITFDPFVYLPVPFPKNKQ 607

  Fly   532 -----FWDI---------------------------------------------------SLDL- 539
                 ||.:                                                   |||:
 Worm   608 STDLIFWPLENQTKPYKLTVSYSTEGTVADFLSVVSETVRVPTRNLRACEAICHKFDKIYSLDMK 672

  Fly   540 ----------------------------------------------------------------- 539
                                                                             
 Worm   673 VSDIVSPDRLFVFQTHDEMEFNEEIVILHVLQRELYRKNTKHACHECGNSKLKLKACEECYDAVY 737

  Fly   540 ----------------------------------------------------------------- 539
                                                                             
 Worm   738 CSKECQVANWSTGGHREECSKRKPSETVGHPLIVSLPRSQLTYQHLYRVLEAKSRHTVTLFQQPQ 802

  Fly   540 ----------------------------------GETTTHGGVT-----------PKT------- 552
                                              ||:::...|:           |:|
 Worm   803 YESEGSEGDSLQAPSRSIKKRNGVGAPPTFLQPPGESSSSSSVSSTPRRRSVAAEPRTKNQKMFE 867

  Fly   553 ----------------------------------------------------------------- 552
                                                                             
 Worm   868 IRKLSGQNDSFGSHSISDDEACQSLESGGYVSVNWINQRNGKPYITIENRKDIDVDVEKSRQMNS 932

  Fly   553 -----------------LIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHL 600
                             |...|:.::..|.|.......|||||...|:||:..|..||.|:...|
 Worm   933 RNMNGYVKSNNSETNPHLTQMLDLFSETERLKPEESWYCSTCKENVEATKKLQLYRLPPVLIIQL 997

  Fly   601 KRFEHSALIDR-------KISSFIQFPVE-FDMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGH 657
            |||.::|...:       |.:..:::|:| .||:||::|.........:.|..||.|.|....||
 Worm   998 KRFVYTAFTYQSSMARRSKDTRSVEYPLESLDMSPFLAETSPHPNSTMYDLTGVVCHSGNSYFGH 1062

  Fly   658 YTAYVR-------HQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 695
            |.:..|       ..|..|...||..:...|...:...:.|||||
 Worm  1063 YISMGRLADFDSSKTKIEWRNFDDSTVARQSTSTLQTEDAYLLFY 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464
		Peptidase_C19D	365..696	CDD:239125	109/693 (16%)
F07A11.4	NP_001364591.1	UBP12	<401..1110	CDD:227847	110/695 (16%)
		zf-MYND	716..756	CDD:460312	0/39 (0%)