Protein Alignment not and duo-3

DIOPT Version :10

• Sequence 1: NP_001401041.1
• Gene: not / 40030
• FlyBaseID: FBgn0013717
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_001293463.1
• Gene: duo-3 / 172925
• WormBaseID: WBGene00001112
• Length: 924
• Species: Caenorhabditis elegans
• Alignment Length: 331
• Identity: 66/331 - (19%)
• Similarity: 113/331 - (34%)
• Gaps: 119/331 - (35%)

  Fly   358 PNQTIGLRGLLNLGATCFMNCIVQALVHTP-LLSDYFMSD--RH----DCGS----------KSS 405
            ||     |.|.|.|.:|:.|..:|||...| |:|.:.|..  ||    :|.|          :|.
 Worm   300 PN-----RRLYNTGNSCYFNSTMQALSSCPSLVSRFEMLHRLRHGNYLECPSYDLRPKFAVFESC 359

  Fly   406 HKCLVCEVSRL----FQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATL----DV 462
            .:.:|....|:    .:|:...|.|...|......|....|.....:|:||||:....|    |:
 Worm   360 LRMMVKLSDRMENPHLKEYRLPSFSETELANTRLKIGRVVKEFDNNDQKDAHEYLTELLSCVDDI 424

  Fly   463 LH------RH-----CVKAKAE---------HESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQ 507
            :.      :|     .::.|.|         ||.||:..|.....:.||:.    ||... :::.
 Worm   425 MQVVPDEIKHLDPLNSIRYKTERSFICFNCGHEEKSSDCGWILPLSISNND----YGIIE-LLES 484

  Fly   508 IFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKI 572
            .|...|:::.:|.:|
 Worm   485 NFKTTLETNKICSSC-------------------------------------------------- 499

  Fly   573 KCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALID-RKISSFIQFPVEFDMTPF-------M 629
               :|::...|.:   :...|..:..:..|:|.:::.| ||.:..|..|:..|:|.|       .
 Worm   500 ---SCENAVSSER---IANFPECLILNPMRYERTSISDYRKDNRQITVPLTLDLTRFGAFASLEQ 558

  Fly   630 SEKKNA 635
            .|.:|:
 Worm   559 DENRNS 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001401041.1	zf-UBP	253..310	CDD:460464
		Peptidase_C19D	365..696	CDD:239125	64/324 (20%)
duo-3	NP_001293463.1	Peptidase_C19Q	303..>554	CDD:239138	61/311 (20%)
		Peptidase_C19	304..>426	CDD:470612	32/121 (26%)
		OTU_CeDUB-like	663..783	CDD:438592
		Peptidase_C19	<812..922	CDD:470612