DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and usp-48

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001361851.1	Gene:	usp-48 / 172782	WormBaseID:	WBGene00009267	Length:	1264	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	77/337 - (22%)
Similarity:	132/337 - (39%)	Gaps:	83/337 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 GLLNLGATCFMNCIVQALVHTP----LLSDYFMSDRHDCGSKSSHKCLVCEVSRL--------FQ 211
            ||:|.|..|::|..:|...:.|    |:.|:          :.|...:..|..|:        .|
Worm   109 GLINGGNFCYVNSFLQVWFNVPEFRQLIYDF----------RPSENFVPPEAPRMNVQATMLALQ 163

  Fly   212 E-FYSGSRSPL-------SLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHE 268
            : ||:...:|.       :|.:||.|         ..||||:.||.:...:.|.| |:   .:|.
Worm   164 DIFYTLQTTPFNETDKTSNLGKLLRL---------NSEQQDSQEFGLKFFNALER-CL---PDHP 215

  Fly   269 SKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLG 333
                   :|..|...              :..:|||...:.:||: |...|...:....::|::.
Worm   216 -------NGKETLKR--------------LKDLFTGETCTRIVCK-CGQRSEREETAISLTLNIE 258

  Fly   334 ETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEH 398
            ...        ||:|.|:.|...|||..   .|||.|....:.:||.....||.|:...|.|:::
Worm   259 GYC--------TLLDALDAYFGEEHLDD---FKCSKCNKTGDVSKQSDYVKLPPVIVIQLNRYKY 312

  Fly   399 SALIDRKISSFIQFPVEFDMTPFMSEKKNAYGDFR-FSLYAVVNHVG-TIDTGHYTAYVR---HQ 458
            ::...:|:.:.:.:|.|.....|.....:...... :.|:||..|.| ..:.|||...::   :|
Worm   313 TSKGRQKLKTPMAYPREIPAKAFQRTNNSIPPPAEMYDLFAVTIHEGNNAECGHYYDLIKSPLNQ 377

  Fly   459 KDTWVKCDDHVI 470
            |  |.:.:|..|
Worm   378 K--WYRYNDEAI 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	77/337 (23%)
usp-48	NP_001361851.1	UCH	108..394	CDD:395355	77/337 (23%)
usp-48	NP_001361851.1	Ubiquitin_like_fold	1161..1264	CDD:421700
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910