DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and AgaP_AGAP012248

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_320294.3	Gene:	AgaP_AGAP012248 / 1280441	VectorBaseID:	AGAP012248	Length:	833	Species:	Anopheles gambiae

Alignment Length:	434	Identity:	87/434 - (20%)
Similarity:	150/434 - (34%)	Gaps:	132/434 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 HITSHLRSKKHNVALEL------SHGTLYCYACRDFIYD----------------ARSREYALIN 113
            |..:|.:...:.:|::|      ..|.:|.|:..|.:.|                ....|.::|.
Mosquito   231 HAVNHYKETNYPLAVKLGTITADGKGDVYSYSEDDMVEDPYLVKHLAHWGINVGQLEKTEKSMIE 295

  Fly   114 RKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVH 178
            .:|   ||.:.||         |..:|..:..:  ::|....|..|:.|||.||::|.::|.|..
Mosquito   296 LEL---DLNQRIG---------EWGILCESGSQ--LKPIAGPGYTGMKNLGNTCYLNSVMQVLFT 346

  Fly   179 TP-----------LLSDYFMSD----------RHDCGSKSSHKCLVCEVSRLFQEFYSGSRSPLS 222
            .|           .:.|.|.||          :...|..|....::.|.|....:..:|..:|..
Mosquito   347 IPDFVRRFVDGSKAIFDSFPSDPANDFNVQMAKLGTGLCSGRYSVLSESSLDTADSSTGGIAPTM 411

  Fly   223 LHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSS 287
            ...   ||.......:..:||||.|||:..:..|.:|     :.|:           ||.|.:..
Mosquito   412 FKA---LIGQGHPDFSTKQQQDAQEFFLHIISTLEKH-----SRHQ-----------TNPSEALR 457

  Fly   288 SHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYD--PFWDISL--------DLGETTTHGG-- 340
            .       ||.|::           :.|:.....|:  ..|.:.|        :|.|...:..
Mosquito   458 F-------CIEDRV-----------ECCSSGKVMYNRRDEWCLPLQIPLQKATNLDEVKQYEAER 504

  Fly   341 ---------------VTPK-TLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVV 389
                           |.|| ||..||:.:.:.|.:............:.:::||   |.::|..:
Mosquito   505 TAAEREGRRLDPDALVRPKITLAACLDTFAQPELVEQFYSTAIGAKTTAKKTTK---LASMPDYL 566

  Fly   390 SFHLKRF----EHSALIDRKISSFIQFPVEFDMTPFMSEKKNAY 429
            ..|||:|    :.::|   |:...|..|...|:.......|..|
Mosquito   567 LLHLKKFTLKEDWTSL---KLDVAIDIPEVLDLETLRGTGKQPY 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999	8/37 (22%)
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	67/325 (21%)
AgaP_AGAP012248	XP_320294.3	UBP14	8..832	CDD:227532	87/434 (20%)
		zf-UBP	198..272	CDD:280334	9/40 (23%)
		Peptidase_C19B	327..831	CDD:239123	67/324 (21%)
		UBA1_UBP5_like	626..669	CDD:270480
		UBA2_UBP5	693..735	CDD:270569
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910