DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and Usp9y

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_683745.2	Gene:	Usp9y / 107868	MGIID:	1313274	Length:	2556	Species:	Mus musculus

Alignment Length:	450	Identity:	97/450 - (21%)
Similarity:	159/450 - (35%)	Gaps:	150/450 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 VRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLL---------------SDYFMSDRHDCGSKSS 198
            |.|....|..||.|.||||:||.::|.|...|.:               .|.|..::.|..:...
Mouse  1550 VGPRPPKGFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIDSIWSDTDDDIFKGEKQDSENNVD 1614

  Fly   199 HKCLVCEVSRLFQEFYSGS----RSPLSLHRLLHL-------------------------IWNHA 234
            .:..|......|::..:.|    |...::..|.||                         :|...
Mouse  1615 PRDDVFRYPHQFEDKPTLSKVEDRKEYNIAVLKHLQITFGHLAASQLQYYVPKGFWQQFRLWGEP 1679

  Fly   235 KHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIID 299
            .:|.  ||.||.|||.:.:|.|. ...||            .|..|                ::.
Mouse  1680 VNLR--EQHDALEFFNSLVDSLD-EAFKA------------LGYPT----------------VLS 1713

  Fly   300 QIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAK 364
            ::..|......:||.|.......:.|..:::|:   ..|     :.|:|.||:|.:.:.|..|..
Mouse  1714 KVLGGSFADQKICQGCPHRYECEESFTTLNVDI---RNH-----QNLLDSLEQYVKGDLLEGANA 1770

  Fly   365 IKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHS-----ALIDRKISSFIQFPVEFDMTPF--- 421
            ..|..|....::.|:..::.||||::..||||::.     |:   |.:.:.:||.|.||.|:
Mouse  1771 YHCEKCDKKVDTVKRLLIKKLPSVLTIQLKRFDYDWERECAI---KFNDYFEFPRELDMEPYTVA 1832

  Fly   422 ------------------MSEKKNAY--GDFRFSLYAVVNHVGTIDTGHYTAYV--RHQKDT--- 461
                              .:|:..:.  |..::.|..|:.|.|..:.|||.:|:  |:.||:
Mouse  1833 GATKLEGDSVNPQTQLIKQNEQSESVIPGSTKYRLVGVLVHSGQANGGHYYSYIIQRNGKDSKRS 1897

  Fly   462 -WVKCDDHVITMASLK----------------QVLDS--------------EGYLLFYHK 490
             |.|.||..:|...:.                :|.|.              ..|:|||.:
Mouse  1898 HWFKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYER 1957

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	93/438 (21%)
Usp9y	NP_683745.2	peptidase_C19C	1557..1960	CDD:239124	95/442 (21%)
Usp9y	NP_683745.2	UCH	1559..1955	CDD:278850	92/437 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910