DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment not and usp36

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_004916402.1	Gene:	usp36 / 100485023	XenbaseID:	XB-GENE-923312	Length:	1000	Species:	Xenopus tropicalis

Alignment Length:	375	Identity:	107/375 - (28%)
Similarity:	182/375 - (48%)	Gaps:	56/375 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 TKETNLLLANAR-------RRLVRPNQTIGLR---------GLLNLGATCFMNCIVQALVHTPLL 182
            |:..|:.|:..|       ::::.|...:.::         ||.|||.|||:|..||.|.:||.|
Frog    80 TQHQNVDLSTGRSDGVPVPQKILFPADKLSMKWDRISRVGAGLQNLGNTCFLNATVQCLTYTPPL 144

  Fly   183 SDYFMSDRHDCGSKSSHKCLVCEV-SRLFQEFYSGSRS--PLSLHRLLHLIWNHAKHLAGYEQQD 244
            ::|.:|..|....:.|..|::|.: :.|.|.|.:...:  |:|..|.|..|   |:|.....|:|
Frog   145 ANYLLSKEHSRNCQQSGFCMLCIMQNHLIQVFANSGNNVKPVSFIRDLKKI---ARHFRFGSQED 206

  Fly   245 AHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSD 309
            ||||...|:|.:.:.|:...|..:..|                     |...::.|||.|.|:|.
Frog   207 AHEFLRYTIDAMQKACLNGYARLDRHS---------------------QATSLVHQIFGGYLRSR 250

  Fly   310 VVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQ 374
            |.|..|..||.||||:.||:|::...        ..::..||.:.:::.|.......|:.||...
Frog   251 VTCSVCKNVSDTYDPYLDIALEIRNV--------PNIVCALEMFVKSDVLSGENAYMCARCKKKV 307

  Fly   375 ESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAYGDFRFSLYAV 439
            .:.|:||:....:|::..||||.:|:  ..||:..:.:|...::.|:||::...  ...::||||
Frog   308 PACKRFSVHRESNVLTLSLKRFANSS--GGKITKEVGYPEFLNLRPYMSQRNGV--PVMYALYAV 368

  Fly   440 VNHVG-TIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 488
            :.|.| :...|||..||:.....|.:.:|.::..:::|.||:.:.|:|||
Frog   369 LVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHASNIKVVLNQQAYVLFY 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	102/344 (30%)
usp36	XP_004916402.1	Peptidase_C19E	119..419	CDD:239126	102/336 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D929408at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010