DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment not and usp47

DIOPT Version :9

Sequence 1:	NP_001287106.1	Gene:	not / 40030	FlyBaseID:	FBgn0013717	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_031755561.1	Gene:	usp47 / 100036690	XenbaseID:	XB-GENE-5760041	Length:	1374	Species:	Xenopus tropicalis

Alignment Length:	444	Identity:	89/444 - (20%)
Similarity:	144/444 - (32%)	Gaps:	173/444 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 GLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHKCLVCEVSRLFQ-EFYSGSRS 219
            |..||:|...||::|.::|.|..||...                       :.|:: ||......
Frog   192 GYVGLVNQAMTCYLNSLLQTLFMTPEFR-----------------------NALYKWEFEESEED 233

  Fly   220 PLS-----LHRLLHLI------------------WNHAKHLAGYEQQDAHEFFIATLDVLHRHCV 261
            |:|     |.||..|:                  |:.::   .::|.|..|......|.|
Frog   234 PVSSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE---AWQQHDVQELCRVMFDAL----- 290

  Fly   262 KAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFW 326
                |.:.|......                    :|:|::.|.|:..|.|..|...|...|.|.
Frog   291 ----EQKWKQTEQAD--------------------LINQLYQGKLKDYVKCLECGYESWRIDTFL 331

  Fly   327 DISL---DLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSV 388
            ||.|   ..|..|..|     ::.:.|:.:.:.|.|....:..|..||...::.|.......|.:
Frog   332 DIPLVIRPFGSNTAFG-----SMEEALQAFIQPETLDGPNQYFCERCKRKCDARKGLKFLHFPYL 391

  Fly   389 VSFHLKR--FEHSALIDRKISSFIQFPVEFDMTPF------------------------------ 421
            ::..|||  |:::::...|::..:.||.|.||:||
Frog   392 LTLQLKRFDFDYTSMHRIKLNDRMTFPDELDMSPFIDVEDEKSPQTDSCTDSGAENEGSCHSDQM 456

  Fly   422 ----------------------------MSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQ 458
                                        :|||.:.|     .|::|:.|.|:...|||.|.::..
Frog   457 SNDFSTDDAVDEGICLETNSNIEKLNKSVSEKNSLY-----ELFSVMVHSGSAAGGHYYACIKSF 516

  Fly   459 KD-TWVKCDD-HV--ITMASLKQVL----------------DSEGYLLFYH-KN 491
            .| .|...:| ||  ||...:|:..                .:..|:|.|. ||
Frog   517 ADGQWYSFNDQHVSRITQEDIKKTYGGSTGNRGYYSSAFASSTNAYMLMYRLKN 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
not	NP_001287106.1	zf-UBP	46..103	CDD:307999
not	NP_001287106.1	Peptidase_C19D	158..489	CDD:239125	85/437 (19%)
usp47	XP_031755561.1	peptidase_C19C	192..571	CDD:239124	89/444 (20%)
usp47	XP_031755561.1	MSCRAMM_ClfB	<834..1029	CDD:411414
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910