DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32199 and CG31021

DIOPT Version :9

Sequence 1:	NP_730347.1	Gene:	CG32199 / 40028	FlyBaseID:	FBgn0052199	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_733392.2	Gene:	CG31021 / 43638	FlyBaseID:	FBgn0051021	Length:	453	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	133/502 - (26%)
Similarity:	222/502 - (44%)	Gaps:	72/502 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLEMEESLKTNLDIYVQEMQSKLDLIKLYQDSLKRVTLTTLEEKEEYVSNPLNAFPMLRRLNQDW 77
            :|.:|.:|..|:..|.::::.|:|||..|.:..........|:.|:|:|||||:|.::|.::|||
  Fly     1 MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDW 65

  Fly    78 PKWLRYIKLAIASKKIKEMEVQLKSAPIDDDLKVALKGMTRIEKFHNLHAEDLTKGVLMGKKLNS 142
            ..|..|::..:|.:.::::|..|...|..:..:.|.:.:..:.:|:.....||   |...::.:|
  Fly    66 VGWQVYMEDLVAPEAVQKVESLLPQLPQKEAFRKAARSVHSLTQFYGYEPADL---VAKDERSSS 127

  Fly   143 -HLTAPDCVALGDYYYNQTQFSGSTHWYRMALRVHTHPRGMIYAKVLGLKRKRIYKKYAKALLKE 206
             ||:..||..||...|.:..:.|:..|.::|...:|..|.......||..|.::|:...:.|||
  Fly   128 LHLSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHRDLFNPLGAPRWQVYRDLGRTLLK- 191

  Fly   207 SLNSDKSKPTPTEKSEWNRLAKEVTREDNYDNVKKLIDEYL-----SGDEKIF-----QEVAARL 261
             ||..                   ...|.|::..:|..:.:     :|..::|     .|....|
  Fly   192 -LNRQ-------------------CAYDAYESALRLNSQNVHLMKEAGQMELFSLRDPMEPILDL 236

  Fly   262 KRKPTKLERGCRGEWPKKSSPELICRYNRDTSAFLKLAPLKLEFLSVQPMILLYHDVLYENEFKS 326
            :.|||.||:.||||.|:... .|.|..|....:||..||:|.|.|...|.|:||...:||.|.:.
  Fly   237 QPKPTVLEKYCRGEVPRHQG-RLTCELNDWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRH 300

  Fly   327 MRDIAMYNGSMIDGWTYVDFDKKGNPKQQDRVVKMIAFQGTT-----APFTLSINRRMADMSGLE 386
            :.:            .|    ::..|  .||....:...|.:     :|....||.|:.||:|:|
  Fly   301 VEN------------AY----ERCPP--NDRFELKLGISGCSISDGYSPVLKRINERILDMAGVE 347

  Fly   387 MRDNMVLYLTNYGLGGHFGKHVDYVELAKRPPDFFADFGGDRIATALIYASDIPLGGTTVFTKLK 451
            ...: ..|:..|.....|.....:....|.|.....:| .|..|..:|:..|:.|||........
  Fly   348 KTWD-TFYIVEYAQLAPFEPFKLFRNSTKFPKLNLMNF-EDVEAKVIIFLKDVTLGGAFTMPNGD 410

  Fly   452 IAVQPKKGSALIWFNLNHAGEPDPLTEHS--VCPVVLGSRWIISKWI 496
            |.||||:|:.||.|...         |||  :||::.|:..::.|:|
  Fly   411 ILVQPKRGNVLITFENE---------EHSTTICPIIEGTGLVMIKFI 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32199	NP_730347.1	P4Ha_N	6..135	CDD:285528	33/121 (27%)
CG32199	NP_730347.1	P4Hc	<369..497	CDD:214780	38/130 (29%)
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	33/120 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.980