Protein Alignment CG32199 and PH4alphaNE2

DIOPT Version :10

• Sequence 1: NP_730347.1
• Gene: CG32199 / 40028
• FlyBaseID: FBgn0052199
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_733378.1
• Gene: PH4alphaNE2 / 43628
• FlyBaseID: FBgn0039783
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 535
• Identity: 147/535 - (27%)
• Similarity: 252/535 - (47%)
• Gaps: 68/535 - (12%)

  Fly     3 YSTSVMSMMKLLEMEESLKTNLDIYVQEMQSKLDLIKLYQDSLKRVTLTTLEEKEEYVS------ 61
            ::.||::|..:|.:|:.|.:|::...:.:..|...||.       .....::.::||.|
  Fly    30 FARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKW-------GVFKMMKRRQEYKSSMEIFA 87

  Fly    62 NPLNAFPMLRRLNQDWPKWLRYIKLAIASKKIKEMEVQLKSAPIDDDLKVALKGMTRIEKFHNLH 126
            ||::.|.::|.:..:|..||.|::..:..:::..::.::...|...|...|.:|:.:::..:.:.
  Fly    88 NPIDTFSLIRHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFDFIDAAEGIRKMQATYQMF 152

  Fly   127 AEDLTKGVLMGKKLNSHLTAPDCVALGDYYYNQTQFSGSTHWYRMALRVHTH------------P 179
            :.|:.||:|.|.:.||.|...||:|:|.:..|.:::..:..|...::..:..            |
  Fly   153 SSDIAKGLLDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQTDMELLRGP 217

  Fly   180 RGMIYAKVLGLKRKRIYKKYAKALLKESLNSDKSKPTPTEKSEWNRLAKEVTREDNYDNVKKLID 244
            :.....::||..:.: .:.:..||....:....|...|....|:..|.|.              |
  Fly   218 KLADLCRILGQVQMK-QRNHEGALQAYQVALKLSPHDPEIYEEYRILEKR--------------D 267

  Fly   245 EYLSGDEKIFQEVAARLKRKPTKLER-----GCRG--EWPKKSSPELICRYNRDTSAFLKLAPLK 302
            ..||..|.|.|:       |....||     .|.|  :.|:..| .|.|.||..||.||:|||:|
  Fly   268 LTLSDIEPIEQD-------KDNSHERLVLPPCCSGRCQVPRNLS-NLYCVYNHVTSPFLQLAPIK 324

  Fly   303 LEFLSVQPMILLYHDVLYENEFKSMRDIAMYNGSMIDGWTYVDFDKKGNPKQQD--RVVKMIAFQ 365
            .|.||:.|.::|.||::.:.|...:|..:..:  |:...| .|.|...:..|.|  |..|.:.:.
  Fly   325 TEILSIDPFVVLLHDMISQKESTLIRTSSKEH--MLPSAT-TDPDASDDETQVDTYRTSKSVWYS 386

  Fly   366 GTTAPFTLSINRRMADMSGLEMRDNMVLYLTNYGLGGHFGKHVDYVELAKRPPDFFADFGG--DR 428
            ......|..|..|:.|.:||:|.......:.||||||.|..|:|.:...|.      .|.|  ||
  Fly   387 SDFNDTTKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKN------RFNGTSDR 445

  Fly   429 IATALIYASDIPLGGTTVFTKLKIAVQPKKGSALIWFNLNHAGEPDPLTEHSVCPVVLGSRWIIS 493
            |||.|.|.:::..||.|.|.:|.:.|.|:.||||.|:||:..|.....:.|:.|||::||:|::|
  Fly   446 IATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMS 510

  Fly   494 KWIHERQQVFKKPCL 508
            |||::..|.|.:||:
  Fly   511 KWINDMGQEFTRPCV 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32199	NP_730347.1	P4Ha_N	6..137	CDD:462433	29/136 (21%)
		P4Hc	<369..497	CDD:214780	51/129 (40%)
PH4alphaNE2	NP_733378.1	P4Ha_N	33..163	CDD:462433	29/136 (21%)
		TPR repeat	175..200	CDD:276809	5/24 (21%)
		TPR_16	176..254	CDD:433202	10/78 (13%)
		NrfG	217..>260	CDD:443378	7/43 (16%)
		TPR repeat	219..249	CDD:276809	4/30 (13%)
		P4Hc	342..513	CDD:214780	60/179 (34%)