DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32199 and CG32201

DIOPT Version :9

Sequence 1:	NP_730347.1	Gene:	CG32199 / 40028	FlyBaseID:	FBgn0052199	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_730346.2	Gene:	CG32201 / 317911	FlyBaseID:	FBgn0052201	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	176/505 - (34%)
Similarity:	290/505 - (57%)	Gaps:	19/505 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YSTSVMSMMKLLEMEESLKTNLDIYVQEMQSKLDLIKLYQDSLKRVTLTTLEEKEEYVSNPLNAF 67
            ||:|.:.::|||::||....||...|.::..|.:.:::|..|:......:|.||.:|||||:|||
  Fly    33 YSSSTVGLLKLLKVEEKFTDNLLNQVDQLGEKFEALRMYLSSVGYELHRSLNEKVQYVSNPINAF 97

  Fly    68 PMLRRLNQDWPKWLRYIKLAIASKKIKEMEVQLKSAPIDDDLKVALKGMTRIEKFHNLHAEDLTK 132
            .:|||.::|.|||..|.|.||.......:...:|..|.|.|:..|:.|:.||||.::|..:||.:
  Fly    98 SLLRRTHEDLPKWHEYFKEAIGEGNQSILVDLVKMVPNDVDMLSAMHGIQRIEKIYDLKIDDLAQ 162

  Fly   133 GVLMGKKLNSHLTAPDCVALGDYYYNQTQFSGSTHWYRMALRVHTHPRGMIYAKVLGLKRKRIYK 197
            |||.|.:.|..||..|.:|:|:..|.|:.:..:..|||:|.:........::.::||...:.:::
  Fly   163 GVLQGVQYNVQLTYRDLIAMGNSMYQQSDYQTAAKWYRIACKRELENPEQLFIQILGDPSEHLHR 227

  Fly   198 KYAKALLKESLNSDKSKPTPTEKSEWNRLAKEVTREDNYDNVKKLIDEYLSGDEKIFQEVAARLK 262
            :|.|:|.|  ..|..|:|:   ||...........::..||:...::| ...|.::.::: .::|
  Fly   228 QYIKSLFK--YGSTTSEPS---KSIEEAFIMVQASQEELDNIMSDLNE-PQNDVEVEKDL-YQVK 285

  Fly   263 RKPTKLERGCRGEWPKKSSPELICRYNRDTSAFLKLAPLKLEFLSVQPMILLYHDVLYENEFKSM 327
            |.|:..|.||||.:.:|::  |:|||....:.||:|||||||.:|:.|.:.:||:|||::|.:.:
  Fly   286 RSPSNCELGCRGLYRQKTN--LVCRYKSTANTFLRLAPLKLEEISLDPFMAMYHEVLYDSEIREL 348

  Fly   328 RDIAMYNGSMIDGWTYVDFDKKGNPKQQDRVVKMIAFQGTTAPFTLSINRRMADMSGLEMRDNMV 392
            :..:|   :|::|:.    .::...:.:|.||: ..:...|:.....||:|:.||:|.....:..
  Fly   349 KGQSM---NMVNGYA----SQRNGTEIRDTVVR-YDWWSNTSLVRERINQRIIDMTGFNFLKDEK 405

  Fly   393 LYLTNYGLGGHFGKHVDYVELAKRPPDFFADFGGDRIATALIYASDIPLGGTTVFTKLKIAVQPK 457
            |.:.|||||.:|..|.||.......|:...  .|||:|:.|.|||::|.||.|||.::.:.|.|:
  Fly   406 LQIANYGLGTYFQPHFDYSSDGFETPNITT--LGDRLASILFYASEVPQGGATVFPEINVTVFPQ 468

  Fly   458 KGSALIWFNLNHAGEPDPLTEHSVCPVVLGSRWIISKWIHERQQVFKKPC 507
            |||.|.||||:..|:||..:.||||||:.|.||.::||:....|:|..||
  Fly   469 KGSMLYWFNLHDDGKPDIRSLHSVCPVLNGDRWTLTKWVPMFPQMFSFPC 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32199	NP_730347.1	P4Ha_N	6..135	CDD:285528	48/128 (38%)
CG32199	NP_730347.1	P4Hc	<369..497	CDD:214780	55/127 (43%)
CG32201	NP_730346.2	P4Ha_N	36..165	CDD:285528	48/128 (38%)
CG32201	NP_730346.2	P4Hc	341..507	CDD:214780	63/175 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461970
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910