DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32199 and P4htm

DIOPT Version :9

Sequence 1:	NP_730347.1	Gene:	CG32199 / 40028	FlyBaseID:	FBgn0052199	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	XP_217285.7	Gene:	P4htm / 301008	RGDID:	1311848	Length:	503	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	87/382 - (22%)
Similarity:	144/382 - (37%)	Gaps:	133/382 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 AKVLGLKRKRIYKKYAKALLKESLNSDKSKPTPTEKSEWNRLAKEVTREDNYDNVKKLIDEYLSG 249
            |::.||:|.:|                    .|||:.|....|..|::.|.:    :|:|:...|
  Rat   164 AQMKGLQRSQI--------------------LPTEEYEEAMSAMRVSQLDLF----QLLDQNHDG 204

  Fly   250 DEKIFQEVAARLKRKPTKLERGCRGEWPKKSSPELICRYNRDTSAFLKLAPLKLEFLSVQPMILL 314
            ..:: :||.|:     |:|.   .|.|   .:||.|    ::..:.:|..|.....||:|
  Rat   205 RLQL-REVLAQ-----TRLG---NGRW---MTPENI----QEMYSAIKADPDGDGVLSLQ----- 248

  Fly   315 YHDVLYENEFKSM--RDIAMYNGSMIDGWTYVDFDKKGNPKQQDRVVK----MIAFQGTTAPFTL 373
                    ||.:|  ||...|              .:.:..:...:|:    ....||..|...:
  Rat   249 --------EFSNMDLRDFHKY--------------MRSHKAESSELVRNSHHTWLHQGEGAHHVM 291

  Fly   374 -SINRRMADMSGL-----EMRDNMVLYLTNYGLGGHFGKHVD----YVE--------LAKRPPDF 420
             :|.:|:..::.|     |:.:  .|.:..||.|||:..|||    |.|        :|.....|
  Rat   292 RAIRQRVLRLTRLSPEIVELSE--PLQVVRYGEGGHYHAHVDSGPVYPETVCSHTKLVANESVPF 354

  Fly   421 FADFGGDRIATALIYASDIPLGGTTVF---------------------------TKLKIAVQPKK 458
            ....   |..|.|.|.:::..||.|||                           .|..:.|:|::
  Rat   355 ETSC---RYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDNVDLRDTRRHCDKGNLRVKPQQ 416

  Fly   459 GSALIWFNL-----NHAGEPDPLTEHSVCPVVLGSRWIISKWIH-----ERQQVFKK 505
            |:|:.|:|.     ...||.|..:.|..|.|..|::||.:.||:     .||.:|::
  Rat   417 GTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQ 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32199	NP_730347.1	P4Ha_N	6..135	CDD:285528
CG32199	NP_730347.1	P4Hc	<369..497	CDD:214780	44/177 (25%)
P4htm	XP_217285.7	EF-hand_7	193..253	CDD:404394	21/92 (23%)
P4htm	XP_217285.7	P4Hc	247..459	CDD:214780	53/243 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343176
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1438683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850