DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32199 and phy-3

DIOPT Version :9

Sequence 1:	NP_730347.1	Gene:	CG32199 / 40028	FlyBaseID:	FBgn0052199	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_507251.2	Gene:	phy-3 / 188624	WormBaseID:	WBGene00004026	Length:	318	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	60/253 - (23%)
Similarity:	98/253 - (38%)	Gaps:	62/253 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 EWPKKSSPELICRYNRDTSAFLKLAPLKLEFLSVQPMILLYHDVLYENE------FKSMRDIAMY 333
            :|.|..|..:...||        :.|:.:|.:|..|.:::|.:::...:      |...||:.:.
Worm    65 KWQKNDSICITYVYN--------MLPVDMEIISWAPTLVIYRNLMSPRQTASFLNFIEQRDLEIQ 121

  Fly   334 ----------------NGSMIDGWTYVDFDKKGNPKQQDRV---VKMIAFQGTTAPFTLSINRRM 379
                            |||.|             |.:...|   :||.| |.......|::....
Worm   122 KTSDFGTSIETTHRRANGSFI-------------PPEDSNVTVEIKMQA-QKRIPGLNLTVAEHF 172

  Fly   380 ADMSGLEMRDNMVLYLTNYGLGGHFGKHVDYVEL-AKRPPDFFADFGGDRIATALIYASDIPLGG 443
            :.:|          ||.    |||:..|.||::. :|:..|::.:..|:||.|.:........||
Worm   173 SALS----------YLP----GGHYAVHYDYLDYRSKQDYDWWMNKTGNRIGTLIFVLKPAEKGG 223

  Fly   444 TTVFTKLKIAVQPKKGSALIWFNLNHAGEPDPLTEHSVCPVVLGSRWIISKWIHERQQ 501
            .|||..:...|:...|.|..|||.....|.:.|:.|..||:..|.:.|.:.||....|
Worm   224 GTVFPSIGSTVRANAGDAFFWFNAQADEEKEMLSNHGGCPIYEGRKVIATIWIRAYNQ 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32199	NP_730347.1	P4Ha_N	6..135	CDD:285528
CG32199	NP_730347.1	P4Hc	<369..497	CDD:214780	35/128 (27%)
phy-3	NP_507251.2	P4Hc	102..277	CDD:214780	48/202 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3137
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1438683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.730