DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18231 and p4htma

DIOPT Version :9

Sequence 1:	NP_649045.2	Gene:	CG18231 / 40026	FlyBaseID:	FBgn0036796	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001074160.1	Gene:	p4htma / 791209	ZFINID:	ZDB-GENE-070112-2222	Length:	478	Species:	Danio rerio

Alignment Length:	340	Identity:	76/340 - (22%)
Similarity:	118/340 - (34%)	Gaps:	121/340 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 SILGDPKVNLYTLYAKSML--IFGMI---KSNPSMTIAEAKKISYEAL-------NKASLADIKS 251
            ||:.|...|:.||..|.:|  |.|.:   :||..|.:|:.|.:::.:|       .:.:..::.|
Zfish   124 SIVPDRTHNMRTLSLKPLLFEIPGFLSVEESNVVMQLAQLKGLTHSSLLTNPDQEEQLTQDELFS 188

  Fly   252 LLN----------ELLS---QTDDEIVYEMNVNK------TKPSD----------------YEIG 281
            ||:          |:||   .||...:...|:.|      |.||.                |...
Zfish   189 LLDLNQDGLLQREEILSLSHSTDGSWLSSYNLRKIHTGLETNPSGVLSLQEFKRVSGGVLRYSGA 253

  Fly   282 CRG-----QFLRRRNHVCTYNFTITEFLKLAPLKQEVLNWDPYIVIYHDVLNDDEIDKLKNHLND 341
            .:|     :..:|..|...|....|..| |..::..|                ..:.:|.:.|.|
Zfish   254 AQGLDGHTKVRQRSTHTRLYLGEGTHHL-LKSVRNRV----------------TRLTRLPSSLVD 301

  Fly   342 -TDAVEVNPIEKRIFQRINELTRLSFEHSDQQIVSKNGPRTHKHKK---------EYLKGTLLFF 396
             ::|:||...|:.:|         |..|.|......:...||.|..         .||  |:|.:
Zfish   302 LSEAMEVVRYEQGVF---------SHAHHDSSPTHPDNSCTHTHLAANTSNQVACRYL--TVLLY 355

  Fly   397 LNNVELGGAMVFP---------------------KLKISVFPQKGSCLFWHN----------TLD 430
            ||:.:.||...||                     |..:.|.|..|:.|.|:|          .||
Zfish   356 LNSADSGGETSFPVADNRTYEEEVLGDLSQQYCDKGNLKVKPVAGTALLWYNHLSDGNGWVGELD 420

  Fly   431 PRSEPLECPVLQGNK 445
            ..|...:|.|.:|.|
Zfish   421 EFSLHGDCLVTRGFK 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18231	NP_649045.2	P4Ha_N	19..148	CDD:285528
CG18231	NP_649045.2	2OG-FeII_Oxy	322..449	CDD:304390	38/165 (23%)
p4htma	NP_001074160.1	2OG-FeII_Oxy	<272..442	CDD:304390	43/192 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583492
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740