DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18231 and P4htm

DIOPT Version :9

Sequence 1:	NP_649045.2	Gene:	CG18231 / 40026	FlyBaseID:	FBgn0036796	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_083220.3	Gene:	P4htm / 74443	MGIID:	1921693	Length:	503	Species:	Mus musculus

Alignment Length:	165	Identity:	42/165 - (25%)
Similarity:	56/165 - (33%)	Gaps:	71/165 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 IEKRIFQRINELTRLS---FEHSDQQIVSKNGPRTHKHKK------------------------- 386
            :.:.|.||:..|||||   .|.|:...|.:.|...|.|..
Mouse   290 VMRAIRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPF 354

  Fly   387 ----EYLKGTLLFFLNNVELGGAMVFP---------------------------KLKISVFPQKG 420
                .|:  |:||:||||..||..|||                           |..:.|.||:|
Mouse   355 ETSCRYM--TVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQG 417

  Fly   421 SCLFWHNTL----------DPRSEPLECPVLQGNK 445
            :.:||:|.|          |..|....|.|.:|.|
Mouse   418 TAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTK 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18231	NP_649045.2	P4Ha_N	19..148	CDD:285528
CG18231	NP_649045.2	2OG-FeII_Oxy	322..449	CDD:304390	42/165 (25%)
P4htm	NP_083220.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..110
		EF-hand_7	193..253	CDD:290234
		EFh	195..253	CDD:298682
		P4Hc	247..459	CDD:214780	42/165 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839382
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740