DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18231 and zgc:152670

DIOPT Version :9

Sequence 1:	NP_649045.2	Gene:	CG18231 / 40026	FlyBaseID:	FBgn0036796	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001070123.2	Gene:	zgc:152670 / 557059	ZFINID:	ZDB-GENE-060929-954	Length:	490	Species:	Danio rerio

Alignment Length:	514	Identity:	120/514 - (23%)
Similarity:	209/514 - (40%)	Gaps:	140/514 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VENNSVYSSITRLLKLLEMEEIFITNIKAYTNKLAEKVKNLQAYIDSVDYEFQQSFEDREKYVGN 75
            :.....:||:.::.:|...||..:.....|.:...|.:|.:::.:..:......:.:..|:.:.:
Zfish    18 ITEQEFFSSVDQVSQLFNEEENLLDTFSLYIDAEEENLKKMKSLLLLLQLGSFSNPQSPEETMRD 82

  Fly    76 PINAFSLVRRTHQDLPKWHN---YSQQ---------------------------IVGMEELFAL- 109
            |:.||.|::|...:   |.|   ::||                           ::|::|::.|
Zfish    83 PVAAFKLLKRLRHE---WVNIAKFTQQSLYQEFQTLLDYSLIPELEDINSAALGLIGLQEIYKLY 144

  Fly   110 -EEIIAKVPDKKDMAYSLGEMHRIEQIYDLEAIELARGRIQGKQYDFRPSIRDCVALGEHKFKRE 173
             ..|..:.|...|.||.:|                                  .||..|.||
Zfish   145 PHNITKETPLSADEAYYIG----------------------------------LVAYEEDKF--- 172

  Fly   174 DYQRASMWFRVAIKHEPEGNAEIINSILGDPKVNLYTLYAKSMLI-FG--MIKSNPSMTIAEAKK 235
              |.|.:||..::....:.::...|.:|.....:.|...:..:.| ||  ::..:||....:.:.
Zfish   173 --QHAFLWFLHSLNRLTDFSSTTKNDLLRFLSSSAYQFGSLPVAIYFGQKLLNLDPSNEEIKVQL 235

  Fly   236 ISYEALNKASLADIKSLLNELLSQTDDEIVYEMNVNKTKPSDYEIGCRGQF-----LRRRNHVCT 295
            ..|..:.              |.:|.:..::.:|....  :.||..|||:.     .|:|...|.
Zfish   236 GLYRLIR--------------LQRTSNPDIFTLNTQSN--NSYEALCRGEVDERTSKRQRALSCR 284

  Fly   296 YNFTIT----EFLKLAPLKQEVLNWD-PYIVIYHDVLNDDEIDKLK-----------------NH 338
            |:   |    ..|..||:|:|.| || |.|:.||||::|.||:.||                 :.
Zfish   285 YS---TGGGNPRLMYAPVKEEEL-WDEPKIIRYHDVISDTEIETLKDIARPELTRSQTGWGVISD 345

  Fly   339 LNDTDAV---EVNPIEKRIFQRINELTRLSFEHSDQQIVSKN--GPRTHKH-----KKEYLKGTL 393
            :..:.:|   ||..: .||.|||.::|.||.|.:::..|...  |.|...|     :......|.
Zfish   346 IRTSQSVFLEEVGTV-ARISQRIADITGLSVESAEKLHVQNYGIGGRYTPHFDTGDEVNERTATF 409

  Fly   394 LFFLNNVELGGAMVFPKLKISVFPQKGSCLFWHN-----TLDPRSEPLECPVLQGNKRV 447
            |.::::||:|||.||..:.::|.|:|||.:||:|     .||.:::...||||.|||.|
Zfish   410 LIYMSDVEVGGATVFTNVGVAVKPEKGSAVFWYNLHKNGELDLKTKHAGCPVLVGNKWV 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18231	NP_649045.2	P4Ha_N	19..148	CDD:285528	26/160 (16%)
CG18231	NP_649045.2	2OG-FeII_Oxy	322..449	CDD:304390	52/158 (33%)
zgc:152670	NP_001070123.2	P4Ha_N	26..150	CDD:285528	21/126 (17%)
zgc:152670	NP_001070123.2	P4Hc	318..474	CDD:214780	48/152 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920