DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18231 and CG9698

DIOPT Version :9

Sequence 1:	NP_649045.2	Gene:	CG18231 / 40026	FlyBaseID:	FBgn0036796	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_651806.2	Gene:	CG9698 / 43629	FlyBaseID:	FBgn0039784	Length:	547	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	124/522 - (23%)
Similarity:	223/522 - (42%)	Gaps:	98/522 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 YSSITRLLKLLEMEEIFITNIKAYTNKLAEKVKNLQAYIDSVDYEFQQSFEDREKYVGNPINAFS 81
            :|||..:.|:...|:..:.:::.:.:...:|:..|:|.:...:.|..::.|....|..:|||.:.
  Fly    26 FSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNEAREWGPSYFESPINKYL 90

  Fly    82 LVRRTHQDLPKWHNYSQQIVGMEELFALEEIIAK--VPDKKDMAYSLGEMHRIEQIYDLEAIELA 144
            |.:|...|..:..|......|.:.|..|.:...:  :||||::..::..:.|::.:|.|:|.:||
  Fly    91 LNKRLTVDWQRVENLMATSTGEKPLTRLRKFRNRETMPDKKELEGAIDGLLRLQYVYRLKAKDLA 155

  Fly   145 RGRIQGKQYDFRPSIRDCVALGEHKFKREDYQRASMWFRVAIKHEPEGNAEIINSILGDPKVNLY 209
            ||.:.|..|..:.:...||.:.....:.:..:.|..|...|......|..|  ..:  .|::...
  Fly   156 RGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAHSWLIEANDRLTGGEKE--EQL--KPQILAL 216

  Fly   210 TLYAKSML------------IFGMIKSNPSMTIAEAKKISYEA-LN----KASLADIKSLLNELL 257
            .:.||..|            :.|:      .:.:|....:||. ||    ||.|.:.|.:|....
  Fly   217 LVQAKKELEDFRGLNDTYQELIGI------QSASEEHAKNYETFLNALSEKALLNESKPILEHAP 275

  Fly   258 SQTDDEIVYEMNVNKTKPSDYEIGCRGQFL---RRRNHV-CTYNFTITE---FLKLAPLKQEVLN 315
            ...:.|.|.|...       |.:.|.|.:.   :.:.|: |.|   :||   ||.:||||.|.|.
  Fly   276 IPEEGEPVGEFQA-------YSLTCSGHWRLTPKEQRHLRCGY---VTETHPFLWIAPLKAEELF 330

  Fly   316 WDPYIVIYHDVLNDDEIDKLK----NHL--------NDTDA------------VEVNPIEKRIFQ 356
            .||.:|:||||:...|||.::    |.|        |::..            |..:.:...|.|
  Fly   331 QDPLLVLYHDVIYQSEIDVIRKLTENRLMRATITSHNESVVSNVRTSQFTFIPVTAHKVLSTIDQ 395

  Fly   357 RINELTRLSFEHSDQQIVSKNGPRTH--KHKKEYLK-----------------GTLLFFLNNVEL 402
            |:.::|.|:.::::....:..|...|  :|...:.:                 .|:||:|::|..
  Fly   396 RVADMTNLNMKYAEDHQFANYGIGGHYGQHMDWFYQTTFDAGLVSSPEMGNRIATVLFYLSDVAQ 460

  Fly   403 GGAMVFPKLKISVFPQKGSCLFWHN-----TLDPRSEPLECPVLQGNK----RVITQKGAYNGRP 458
            ||...||:|:..:.|:|.:..||||     ..|.|::...||::.|:|    |.|.:....:.||
  Fly   461 GGGTAFPQLRTLLKPKKYAAAFWHNLHASGVGDVRTQHGACPIIAGSKWVQNRWIRENDQSDRRP 525

  Fly   459 MQ 460
            .:
  Fly   526 CE 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18231	NP_649045.2	P4Ha_N	19..148	CDD:285528	32/130 (25%)
CG18231	NP_649045.2	2OG-FeII_Oxy	322..449	CDD:304390	42/178 (24%)
CG9698	NP_651806.2	P4Ha_N	28..159	CDD:285528	32/130 (25%)
CG9698	NP_651806.2	P4Hc	345..516	CDD:214780	38/170 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900