DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18231 and CG31016

DIOPT Version :9

Sequence 1:	NP_649045.2	Gene:	CG18231 / 40026	FlyBaseID:	FBgn0036796	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001263119.1	Gene:	CG31016 / 326113	FlyBaseID:	FBgn0051016	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	521	Identity:	150/521 - (28%)
Similarity:	229/521 - (43%)	Gaps:	116/521 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YVENNSVYSSITRLLKLLEMEEIFITNIKAYTNKLAEKVKNLQAYIDSVDYEFQQSFED----RE 70
            |.:..:...|:...:.|||.:...|..:.:|..:|.||:..|:..:.    ||:|..|.    .|
  Fly    22 YRDRQNYVISVEEKMDLLEKDRELIIVLDSYATELNEKIIMLKRIVK----EFKQPLEKAKNREE 82

  Fly    71 KYVGNPINAFSLVRRTHQDLPKWHNYSQQIVGMEELFALEEIIAKVPDKKDMAYSLGEMHRIEQI 135
            :|:.|||::.||:|:.|:|..|.....::.||.|::..:|::...:|.:.|:..:...|.||...
  Fly    83 EYLSNPIDSLSLMRQMHEDWEKVEKLLKKPVGQEKIALVEKMREDLPVENDLMEANQAMFRILHT 147

  Fly   136 YDLEAIELARGRIQGKQYDFRPSIRDCVALGEHKFKREDYQRASMWFRVA---IKHEPEGNAEII 197
            ||||..:::.|.|.|.||..:.|..||..:|...|....||.||.|...|   :..:|....|
  Fly   148 YDLEPKDVSAGWIDGVQYGGKMSASDCFTMGTFSFMAGSYQIASKWLSAAKDLLVDQPRKYHE-- 210

  Fly   198 NSILGDPKVNLYTLYAKSMLIFGMIKSNPSMTIAEAKKISYEALNKASLADIKSLLNELLSQTDD 262
              ::|..|.::..|.|:|::..|.:                      |:|....:.:.:..:...
  Fly   211 --VMGITKADVTLLLARSLIASGNV----------------------SIATDMLMRDFMFGEAGS 251

  Fly   263 EIVYEMNVNKTKPS----------DYEIGCRGQFLRR-------RNHVCTYNFTITEFLKLAPLK 310
            .:......||.|||          .:...||....|:       |.| |.||...|.||||||.:
  Fly   252 ALTVHFLRNKPKPSINLESWESDESFNQLCRSSSRRQMGESKPSRLH-CRYNTITTPFLKLAPFR 315

  Fly   311 QEVLNWDPYIVIYHDVLNDDEIDKLK---------------------------------NHLN-D 341
            .|.|:.|||::.||:||:|.||:|||                                 .|.| |
  Fly   316 MEELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAKVFRVEKGSDEIDPSRSADGAWLPHQNID 380

  Fly   342 TDAVEVNPIEKRIFQRINELTRLSFEHSDQQIVSKNGPRTH--KHKKEYLK-------------G 391
            .|.:||   ..||.:||.::|.|:.....:....|.|...|  .| .:|..             .
  Fly   381 PDDLEV---LNRIGRRIEDMTGLNTRSGSKMQFLKYGFGGHFVPH-YDYFNSKTFSLETVGDRIA 441

  Fly   392 TLLFFLNNVELGGAMVFPKLKISVFPQKGSCLFWHNTLDPRSEPLE-------CPVLQGNKRVIT 449
            |:||:||||:.|||.|||||.::|..||||.||||| :|.:|...:       ||::.|.|.|:|
  Fly   442 TVLFYLNNVDHGGATVFPKLNLAVPTQKGSALFWHN-IDRKSYDYDTRTFHGACPLISGTKLVMT 505

  Fly   450 Q 450
            :
  Fly   506 R 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18231	NP_649045.2	P4Ha_N	19..148	CDD:285528	39/132 (30%)
CG18231	NP_649045.2	2OG-FeII_Oxy	322..449	CDD:304390	59/182 (32%)
CG31016	NP_001263119.1	P4Ha_N	31..160	CDD:285528	39/132 (30%)
CG31016	NP_001263119.1	P4Hc	333..508	CDD:214780	56/179 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461886
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900