Protein Alignment CG18233 and P4ha1

DIOPT Version :10

• Sequence 1: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_742059.2
• Gene: P4ha1 / 64475
• RGDID: 621000
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 154/524 - (29%)
• Similarity: 257/524 - (49%)
• Gaps: 60/524 - (11%)

  Fly    31 YSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHNEREKFVSNPLNAF 95
            :.:|:..:..|:..|::.:.:...|....::|::.:..:.:.|.|.......:.|.||.:|:|||
  Rat    21 FFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAF 85

  Fly    96 GLIRRLNQDWPKLQNYTQKPLG---LEQLTAMQDIVSAAPESFDMNEKLKAMHRIETTYDLQPKD 157
            .|::|||.:|.:|:|...|.:.   :..||..:...   |...|.....||:.|::.||:|....
  Rat    86 KLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYF---PNDEDQVGAAKALFRLQDTYNLDTNT 147

  Fly   158 IAKGLLQRTEFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQEALKLSTDGSLEIMNRLKEIELKG 222
            |:||.|...:....|...||..|....:...::..:.||.::||....:|.:..::::..::...
  Rat   148 ISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALMQLEEGEMSTVDKVSVLDYLS 212

  Fly   223 FATAVAKRSIYLSNQG-------LTNETIDDMANSQLQDAKLMDLEQLISSEL---KQWINDDS- 276
            :|       :|  .||       ||.:.::.....|..:..|:..|.::|.|.   |....|.|
  Rat   213 YA-------VY--QQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSD 268

  Fly   277 --TTPP------------TDHNLGCRG----LFPKK-SNLVCRY-NSSTNAFLKLAPLKMEEISR 321
              |||.            ..:.:.|||    :.|:: ..|.||| :.:.|....|||.|.|:...
  Rat   269 QKTTPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWD 333

  Fly   322 DPYIVMFHEVISDKDIEEMKGEITEMENGWTSLGDPK--EIVSRVYWIRKESSFS-------KRI 377
            .|.|:.||::|||.:||.:| ::.:......::.||:  ::.:..|.:.|.:..|       .||
  Rat   334 KPRIIRFHDIISDAEIEIVK-DLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRI 397

  Fly   378 NQRISDMTGFKLEEFPAIQLANFGVGGYFKPHYDFYTDRLKEVDVNNTL--GDRIGSIIFYAGEV 440
            |.||.|:||..:.....:|:||:||||.::||:||  .|..|.|....|  |:||.:.:||..:|
  Rat   398 NMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDF--ARKDEPDAFRELGTGNRIATWLFYMSDV 460

  Fly   441 SQGGQTVFPDLKVAVEPKKGNALFWFNAFDDSTPDPRSLHSVCPVLVGSRWTITKWLHYAPQLFV 505
            |.||.||||::..:|.||||.|:||:|.|.....|..:.|:.||||||::|...||||...|.|.
  Rat   461 SAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFR 525

  Fly   506 KPCS 509
            :||:
  Rat   526 RPCT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..164	CDD:462433	35/132 (27%)
		P4Hc	333..498	CDD:214780	67/175 (38%)
P4ha1	NP_742059.2	P4Ha_N	24..155	CDD:462433	36/133 (27%)
		TPR	205..238		6/41 (15%)
		P4Hc	345..518	CDD:214780	67/175 (38%)