Protein Alignment CG18233 and p4ha2

DIOPT Version :10

• Sequence 1: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: XP_012814344.2
• Gene: p4ha2 / 493342
• XenbaseID: XB-GENE-957618
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 149/523 - (28%)
• Similarity: 253/523 - (48%)
• Gaps: 73/523 - (13%)

  Fly    38 LVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHNEREKFVSNPLNAFGLIRRLN 102
            :..|:..|::.:.:...|....:|::..:..:...:...:.::..:.|.::.:|:||:.|::|.|
 Frog    30 MTDLIFRERDLLQSLKEYIREEEERLSKIKRWASEVDELSSRSTADPEGYLGHPVNAYKLVKRFN 94

  Fly   103 QDWPKLQNYTQKPLGLEQLTAMQDIVSA-----------APESFDMNEKLKAMHRIETTYDLQPK 156
            .||..|:|           ..:||....           .|...|.....:|:.||:.||.|.|.
 Frog    95 TDWSSLEN-----------LVLQDSAKGFIANFTFQREYFPTEEDETGAARALMRIQDTYKLDPD 148

  Fly   157 DIAKGLLQRTEFNYRLLFRDCLA---LAYHKFEIGEFKRSLLWFQEALKLSTDGSLEIMNRLKEI 218
            .||||.|..|.:...|...|...   :|||.   |::..::||.|:|||...:|...::|::..:
 Frog   149 VIAKGKLPGTNYISSLSADDSFGMGKIAYHD---GDYYHTVLWMQQALKQMDEGEDAVVNKVDVL 210

  Fly   219 ELKG---FATAVAKRSIYLSNQGLTNETIDDMANSQLQDAKLMDLEQLISSELKQWINDDSTTPP 280
            :...   |......|::.|:.:.|..:...|.|.:.|:..:.|..:|  .:||||  |:.:.|..
 Frog   211 DYLSYTVFQLGDVPRALELTKRLLALDPNHDRAVNNLKYFEKMQEKQ--KAELKQ--NESTNTES 271

  Fly   281 TDHNLG------------------CRG----LFPKKS-NLVCRY-NSSTNAFLKLAPLKMEEISR 321
            .....|                  |||    :.|::. .|.||| |.:.:.:|.|:|:|:|:...
 Frog   272 ATRQPGVYSRPLDYLPERDVYEALCRGEGVKMNPRRQRRLFCRYHNGNRSPYLILSPVKVEDEWD 336

  Fly   322 DPYIVMFHEVISDKDIEEMKGEITEMENGWTSLGDPKE--------IVSRVYWIRK-ESSFSKRI 377
            .|.||.:...:||::|.::| |:.:.:....::.|||.        .||:..|:.: :.....|:
 Frog   337 SPRIVRYLNALSDEEIAKIK-ELAKPKLARATVRDPKTGVLSVANYRVSKSAWLEENDDPVIARV 400

  Fly   378 NQRISDMTGFKLEEFPAIQLANFGVGGYFKPHYDFYTDRLKEVDVNNTL--GDRIGSIIFYAGEV 440
            |.|:..:||..::....:|:||:|:||.::||:||  .|..|.||...|  |:|:.:.:.|..:|
 Frog   401 NLRMQAITGLTVDTAELLQVANYGMGGQYEPHFDF--SRKDEPDVFKRLGTGNRVATFLNYMSDV 463

  Fly   441 SQGGQTVFPDLKVAVEPKKGNALFWFNAFDDSTPDPRSLHSVCPVLVGSRWTITKWLHYAPQLFV 505
            ..||.|||||...|:.||||.|:||:|.|.....|.|:.|:.|||||||:|...||.|...|.|:
 Frog   464 EAGGATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWFHERGQEFL 528

  Fly   506 KPC 508
            :||
 Frog   529 RPC 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..164	CDD:462433	30/136 (22%)
		P4Hc	333..498	CDD:214780	65/175 (37%)
p4ha2	XP_012814344.2	P4Ha_N	26..157	CDD:462433	31/137 (23%)
		BepA	166..>247	CDD:443813	19/83 (23%)
		TPR repeat	166..201	CDD:276809	12/37 (32%)
		TPR repeat	206..236	CDD:276809	4/29 (14%)
		P4Hc	348..521	CDD:214780	65/175 (37%)