Protein Alignment CG18233 and PH4alphaNE1

DIOPT Version :10

• Sequence 1: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 543
• Identity: 145/543 - (26%)
• Similarity: 249/543 - (45%)
• Gaps: 64/543 - (11%)

  Fly     4 VVRAAAVLILVQSIHSTDPNDFLNRKYYSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNI 68
            |:....:.:|.|...::|         |.||:.||..||..||..........|.:|..:..|..
  Fly     5 VLLVGLIFLLAQGSLASD---------YFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLES 60

  Fly    69 FLDALKRPNHKTHNEREKFVSNPLNAFGLIRRLNQDWPKLQNYTQKPLGLEQLTAMQDIVSAAPE 133
            .|.::::.:....::.|.:::||:|.:.|::||:.||..::...|.........|.::...:.|.
  Fly    61 ELSSIEKEHTMAASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEMNFNATREYGLSYPS 125

  Fly   134 SFDMNEKLKAMHRIETTYDLQPKDIAKGLLQRTEFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQ 198
            ..|:.....|:.|:::||.|....:|:|:|...::...:.::||..|....||:.::..:.:|.:
  Fly   126 QEDVEGAALALVRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLR 190

  Fly   199 EALKLSTDGSLEIMNRLKEIELKGFATAVAKRSIYLSNQGLTNETIDDMANSQLQDAKLMDLEQL 263
            |        |:|.:.|.........|......::.|:....|.:::..:.:..........:.|.
  Fly   191 E--------SMERLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQF 247

  Fly   264 ISSELKQW-INDDSTTPPTD------------HNLG---------CRG-LFP-KKSNLVCRYNSS 304
            ....::.| :.|..|.||.|            ::|.         ||| :.| .:..|.|||:..
  Fly   248 DPKRIRNWHLGDKGTAPPEDIDDVYLPKHSDSYSLSQEFAKYEKVCRGEVHPIVRQELRCRYSRG 312

  Fly   305 TNAFLKLAPLKMEEISRDPYIVMFHEVISDKDIEEM---------KGEITEMENGWTSLGDPKEI 360
            .:.:..|||||:||.|.|||:..||:::|...|.::         :..:..:..|  .|......
  Fly   313 NHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGG--QLKKSAFR 375

  Fly   361 VSRVYWIRKESSFSK-RINQRISDMTGFKLEEFPAIQLANFGVGGYFKPHYDFYTD----RLKEV 420
            ||:..|:..||..:. .:.:.:.|.||........:|:||:||||:::||:||:.|    ..:|
  Fly   376 VSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEE- 439

  Fly   421 DVNNTLGDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKGNALFWFNAFDDSTPDPRSLHSVCPV 485
                  |:||.:.|||..||.|||.|.||.|.:||:|:.||.|||:|.......|.|:.|:.|||
  Fly   440 ------GNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPV 498

  Fly   486 LVGSRWTITKWLHYAPQLFVKPC 508
            |.||:|....|:|...|.|.:||
  Fly   499 LKGSKWIGNVWIHEVTQTFARPC 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..164	CDD:462433	31/129 (24%)
		P4Hc	333..498	CDD:214780	60/178 (34%)
PH4alphaNE1	NP_733374.1	P4Ha_N	26..157	CDD:462433	32/130 (25%)
		P4Hc	341..511	CDD:214780	60/178 (34%)