Protein Alignment CG18233 and PH4alphaSG2

DIOPT Version :9

• Sequence 1: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 146/518 - (28%)
• Similarity: 255/518 - (49%)
• Gaps: 60/518 - (11%)

  Fly    27 NRKYYSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHNEREK---FV 88
            |.::| |||..:..|.::|:|.:.....|....|:::|....:::.:|| .|:....:.|   ::
  Fly    22 NGEFY-SSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKR-EHEWATSQLKLDDYL 84

  Fly    89 SNPLNAFGLIRRLNQDW------PKLQNYTQKPLGLEQLTAMQDIVS---AAPESFDMNEKLKAM 144
            .:||:||.||:||.:||      |.|.|..:     |:..|..:::|   ..|:..::...:|.:
  Fly    85 GHPLHAFRLIKRLVRDWDSLIFEPILANNAR-----EEFRAFVEVLSRDLGYPDQSELQGAIKGL 144

  Fly   145 HRIETTYDLQPKDIAKGLLQRTEFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQEALKLSTDGSL 209
            .|::..|:|...|:|.|::....:...|.:|:|..:....|::||::|||.|.|.|..|..:...
  Fly   145 ARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQVAFILLRNSPR 209

  Fly   210 E------IMNRLKE-IELKGFATAVAKRSIYLSNQGLTNETIDDMANSQLQDAKLMDLEQLISSE 267
            |      .::.::| ..:..|.....|::..|.:|.|.::.    .:|..|..|.  ||..:..:
  Fly   210 EEKDADHYLSDIREYASMANFELGNPKKAARLLSQILESQP----THSAQQTQKY--LESRVPGK 268

  Fly   268 LKQWINDDSTTPP--TDHNLGCRG-LFPKKSN---LVCRYNSSTNAFLKLAPLKMEEISRDPYIV 326
                 |...|.|.  :::...|:| ..|::.:   |.|..:...:|:..||||::|.:..||.|.
  Fly   269 -----NVQETKPSWFSNYTRLCQGRRLPEERSGDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDIN 328

  Fly   327 MFHEVISDKDI---------EEMKGEITEMENGWTSLGDPKEIVSRVYWIRKESSFSKRINQRIS 382
            ::|.::|.|.|         |||.........|..::.|.:  ||:..|:..:|.....:.:.|.
  Fly   329 VYHGMLSSKQILSIFEEADKEEMVRSAVAGSGGEGTVRDLR--VSQQTWLDYKSPVMNSVGRIIQ 391

  Fly   383 DMTGFKLEEFPAIQLANFGVGGYFKPHYDFYTDRLKEVDV-NNTLGDRIGSIIFYAGEVSQGGQT 446
            .::||.:.....:|:||:||||.::||.|::     ||:: .|..||||.:.:||..:|.|||.|
  Fly   392 FVSGFDMAGAEHMQVANYGVGGQYEPHPDYF-----EVNLPKNFEGDRISTSMFYLSDVEQGGYT 451

  Fly   447 VFPDLKVAVEPKKGNALFWFNAFDDSTPDPRSLHSVCPVLVGSRWTITKWLHYAPQLFVKPCS 509
            ||..|.|.:.|.||..:.|.|.......|.|:||:.|||:|||:.....|:|...|.|.:||:
  Fly   452 VFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGNIWMHSGYQEFRRPCN 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..163	CDD:285528	36/140 (26%)
		ATP-synt_B	<198..278	CDD:304375	16/86 (19%)
		P4Hc	333..498	CDD:214780	59/174 (34%)
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	36/140 (26%)
		P4Hc	335..503	CDD:214780	59/174 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461761
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910