Protein Alignment CG18233 and CG4174

DIOPT Version :10

• Sequence 1: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_730342.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 136/494 - (27%)
• Similarity: 226/494 - (45%)
• Gaps: 91/494 - (18%)

  Fly    39 VKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHNEREKFVSNPLN---AFGLIRR 100
            :.|||:::..:.|...|..:|::       .|..::|...::....:...::|.|   .:.::|.
  Fly    37 LSLLKLKETHVNNLQSYKKVLKK-------HLQKIRRAIRQSEELLKSTKTSPRNLIYGYKVLRH 94

  Fly   101 LNQDWPKLQNYTQKPLGLEQLTAMQDIVSAAPESFDMNEKLKAMHRIETTYDLQPKDIAKGLLQR 165
            |:.|||:.....:|.|||||:...|.:::..|.|.|..|.:.||||::|.|:|....:.:|.:..
  Fly    95 LHNDWPQYFRLLKKDLGLEQIAVSQMLLTQQPTSVDFEESMGAMHRLQTVYNLDSYAMTEGFIDD 159

  Fly   166 TEFNYRLLFRD-CLALAYHKFEIGEFKRSLLWFQEALKLSTDG-SLEIMNRLKEIELKGFATAVA 228
            .:.|.|....| ||.|......:.::.:|..|.:.||....|. |.|::    :|:|..:...:
  Fly   160 KDKNIRNWSADECLMLGLMYLFLKDYNQSENWLELALYHYDDNVSPEVL----KIKLWNYPNLL- 219

  Fly   229 KRSIYLSNQGL---------TNETIDDMANSQLQDAKLMDLEQLISSELKQWINDDSTTPPTDHN 284
             .|:..:|:||         .||.:....|......:|..|:.|.|:..|      .|.|.....
  Fly   220 -ESLVEANKGLGHYFEAKKYANELLSINPNHTYMLTQLPKLKHLQSNPAK------LTKPKKVFQ 277

  Fly   285 LG---CRGLFPKKSN-LVCRYNSSTNAFLKLAPLKMEEISRDPYIVMFHEVISDKDIEEMKG--- 342
            |.   |...:.:||. |||||...| .|||||||||||:|..|||.:|:..:..||||.:|.
  Fly   278 LQKEICSKRYRRKSGVLVCRYVDWT-PFLKLAPLKMEELSMKPYISIFYGFLGQKDIEVLKNVSR 341

  Fly   343 -EITEME-----------NGWTSLGDPKEIVSRVYWIRKESSFSKRINQRISDMTGFKLEEFPAI 395
             ::..:|           |..|||.|   :|             :::|:.|..:|||.|:....:
  Fly   342 PKLQRIEHLSGNCSCKIGNLSTSLHD---VV-------------RKVNELILGITGFPLKGNQML 390

  Fly   396 QLANFGVGGYFKPHYDFYTDRLKEVDVNNTLGDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKG 460
            ::.|:|:.|.:.|         :|..::|    :..:.||.: ...:||:.|||...:.|.|:||
  Fly   391 EVINYGIAGNYNP---------EEPKIHN----KANAFIFLS-NAGKGGEIVFPSRHLKVRPRKG 441

  Fly   461 NALFWFNAFDDSTPDPRSL-HSVCPVLVGSRWTITKWLH 498
            :.|.|.|.       .:|| :..||:|.|:.|...|.|:
  Fly   442 SMLVWENL-------KKSLIYHQCPILKGNMWVANKVLN 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..164	CDD:462433	34/127 (27%)
		P4Hc	333..498	CDD:214780	46/180 (26%)
CG4174	NP_730342.2	P4Ha_N	33..159	CDD:462433	34/128 (27%)
		TPR repeat	169..197	CDD:276809	7/27 (26%)
		TPR repeat	202..245	CDD:276809	10/48 (21%)
		PLN00052	311..>470	CDD:177683	54/195 (28%)