Protein Alignment CG18233 and p4ha2

DIOPT Version :10

• Sequence 1: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: XP_005173949.1
• Gene: p4ha2 / 373132
• ZFINID: ZDB-GENE-030827-1
• Length: 542
• Species: Danio rerio
• Alignment Length: 553
• Identity: 158/553 - (28%)
• Similarity: 268/553 - (48%)
• Gaps: 69/553 - (12%)

  Fly     7 AAAVLILVQSIHSTDPNDFLNRKYYSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLD 71
            ||.::.|:.::..:.|    .|....:|:..:..|:..|:|.:.:...|....::|::.:..:.:
Zfish     2 AAFLVFLLSTLSFSSP----TRAEIFTSIGQMTNLIFTERELVQSLKEYIQAEEQKLETVRSWAN 62

  Fly    72 ALKRPNHKTHNEREKFVSNPLNAFGLIRRLNQDWPKLQNYTQKPLGLEQLTAMQDIVSAAPESFD 136
            .|.:....:.::.|.|:::|:||:.|::|||.:|.:|::...:......::.|.......|:..|
Zfish    63 KLDKLTRTSTSDPEGFLAHPVNAYKLMKRLNTEWSELESLVLQDPSDGFISNMSVHRQYFPDEED 127

  Fly   137 MNEKLKAMHRIETTYDLQPKDIAKGLL--QR----TEFNYRLLFRDCLALAYHKFEIGEFKRSLL 195
            .....||:.|::.||.|..:..:||.|  ||    ..:|..|...||..:....:...::..|:|
Zfish   128 EKGAAKALLRLQDTYKLDAESFSKGKLPGQRQHSGVRYNALLTVDDCFDMGKMAYNDNDYYHSVL 192

  Fly   196 WFQEALKLSTDG------SLEIMNRLKEIELKGFATAVAKRSIYLSNQGLTNETIDDMANSQLQD 254
            |.|::|:....|      ..::::.|   ....:......|:|.|:.:.|   .||  .:.|...
Zfish   193 WMQQSLRQMDSGEEAKTPKADVLDYL---SYSVYQMGDLPRAIELTRRLL---AID--PSHQRAG 249

  Fly   255 AKLMDLEQLISSELKQWINDDSTTP-PTD---------------------HNLGCRG-----LFP 292
            ..|...|:|:|.||:   :...|.| |.|                     :...|||     ...
Zfish   250 GNLRYFERLLSKELQ---DSGQTQPEPADERPIQLDTYQRPKDYLPEREAYEALCRGEGVKMTTK 311

  Fly   293 KKSNLVCRY-NSSTNAFLKLAPLKMEEISRDPYIVMFHEVISDKDIEEMKGEITEMENGWTSLGD 356
            ::|.|.||| :.:.|..|.|.|:|.|:....|:||.|.|.:||::|:::| ||...:....::.|
Zfish   312 RQSRLFCRYRDGNRNPRLLLKPMKEEDEWDSPHIVRFLEALSDEEIQKIK-EIATPKLARATVRD 375

  Fly   357 PKE--------IVSRVYWIRKESS-FSKRINQRISDMTGFKLEEFPAIQLANFGVGGYFKPHYDF 412
            ||.        .||:..|:..|.. ...|:||||.|:||..::....:|:||:||||.::||:||
Zfish   376 PKTGVLTVAHYRVSKSAWLEGEDDPVIARVNQRIEDITGLTVDTAELLQVANYGVGGQYEPHFDF 440

  Fly   413 YTDRLKEVDVNNTL--GDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKGNALFWFNAFDDSTPD 475
              .|..|.|...:|  |:|:.:.:.|..:|..||.|||||...:|.|:||.|:||:|.|.....|
Zfish   441 --SRKDEPDAFKSLGTGNRVATYLNYMSDVEAGGATVFPDFGASVWPRKGTAVFWYNLFRSGEGD 503

  Fly   476 PRSLHSVCPVLVGSRWTITKWLHYAPQLFVKPC 508
            .|:.|:.|||||||:|...||:|...|.|.:||
Zfish   504 YRTRHAACPVLVGSKWVSNKWIHERGQEFRRPC 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..164	CDD:462433	30/131 (23%)
		P4Hc	333..498	CDD:214780	69/175 (39%)
p4ha2	XP_005173949.1	P4Ha_N	25..156	CDD:462433	30/130 (23%)
		NrfG	177..280	CDD:443378	24/113 (21%)
		P4Hc	353..526	CDD:214780	69/175 (39%)